Purpose: The primary aim of this research was to determin whether the use of oral ketamine is effective, safe, and acceptable fo patients presenting with low-back pain.It was used in conjunctio with acupuncture treatment to reduce the number of the seat(when treating a patient with acupuncture, they receive treatment over a series of days—this may mean every day or every othe day for a period of 10 d, for example, this is called a "seat") o acupuncture.Results: The results showed that(1) 58%(29/50) of the patients became pain-free;(2) 26%(13/50) of the patients experienced a decrease in pain by one half.They continued on acupuncture only, without ketamine;(3) The remaining 16%(8/50) had no response during the 1st course.Among these eight participants, six requested ketamine in combination with acupuncture, and two required surgery.The result of this study is compared with other studies in which acupuncture alone was used in treatment of the 30 patients in the control group.Thirty percent were pain-free after the 1st course of acupuncture, 50% of the patients had pain reduced by one half, and only 20% showed no response during the first course.