Spermatogonial Stem Cell Self-renewal and Differentiation

被引：0
|
作者：
Li-Huan Cao [1 ]
Qiao-Li Zhang [1 ]
Xin-Hua Lin [1 ]
机构：
[1] State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University
来源：
生殖与发育医学（英文） | 2017年 / 1卷 / 03期
关键词：
Differentiation; Self-renewal; Spermatogonial Stem Cells;
D O I：
暂无
中图分类号：
R321.1 [生殖细胞];
学科分类号：
071008 ;
摘要：
Mammalian spermatogenesis is a complicated and precisely controlled process that requires spermatogonial stem cells(SSCs). SSCs maintain the stem cell pool, balance self-renewal–commitment with differentiation, and produce millions of sperm daily. Self-renewal and differentiation are controlled by intrinsic factors within SSCs and extrinsic factors from the "niche." In this review, we discuss the biology of SSCs and the factors regulating their self-renewal and differentiation.
引用
收藏
页码：171 / 178
页数：8
相关论文
共 50 条
  • [41] Regulation of self-renewal and differentiation by the intestinal stem cell niche
    Trevor M. Yeung
    Luis A. Chia
    Cynthia M. Kosinski
    Calvin J. Kuo
    Cellular and Molecular Life Sciences, 2011, 68 : 2513 - 2523
  • [42] CONTROL OF SPERMATOGONIAL STEM CELL SELF-RENEWAL THROUGH CELL-EXTRINSIC FACTORS IN VITRO
    Nagano, Makoto
    Ebata, Kevin
    Yeh, Jonathan
    Zhang, Xiangfan
    JOURNAL OF ANDROLOGY, 2009, 30 : 25 - 26
  • [43] Molecular regulation of spermatogonial stem cell renewal and differentiation
    Makela, Juho-Antti
    Hobbs, Robin M.
    REPRODUCTION, 2019, 158 (05) : R169 - R187
  • [44] Akt mediates self-renewal division of mouse spermatogonial stem cells
    Lee, Jiyoung
    Kanatsu-Shinohara, Mito
    Inoue, Kimiko
    Ogonuki, Narumi
    Miki, Hiromi
    Toyokuni, Shinya
    Kimura, Tohru
    Nakano, Toru
    Ogura, Atsuo
    Shinohara, Takashi
    DEVELOPMENT, 2007, 134 (10): : 1853 - 1859
  • [45] Lovastatin promotes the self-renewal of murine and primate spermatogonial stem cells
    Li, Chaohui
    Yao, Zhaokai
    Ma, Linzi
    Song, Xiuling
    Wang, Wen
    Wan, Cong
    Ren, Shaofang
    Chen, Dingyao
    Zheng, Yi
    Zhu, Yong-tong
    Chang, Gang
    Wu, Shihao
    Miao, Kai
    Luo, Fang
    Zhao, Xiao-Yang
    STEM CELL REPORTS, 2023, 18 (04): : 969 - 984
  • [46] Bisphenol Analogs Downregulate the Self-Renewal Potential of Spermatogonial Stem Cells
    Kim, Seo-Hee
    Shin, Seung Hee
    Kim, Seok-Man
    Jung, Sang-Eun
    Shin, Beom-Jin
    Ahn, Jin Seop
    Lim, Kyoung Taek
    Kim, Dong-Hwan
    Lee, Kichoon
    Ryu, Buom-Yong
    WORLD JOURNAL OF MENS HEALTH, 2025, 43 (01): : 154 - 165
  • [47] TGFβ family signaling in human stem cell self-renewal and differentiation
    Liu, Sijia
    Ren, Jiang
    Hu, Yanmei
    Zhou, Fangfang
    Zhang, Long
    CELL REGENERATION, 2024, 13 (01)
  • [48] MicroRNA regulation of murine trophoblast stem cell self-renewal and differentiation
    Saha, Sarbani
    Ain, Rupasri
    LIFE SCIENCE ALLIANCE, 2020, 3 (11)
  • [49] Human trophoblast stem cell self-renewal and differentiation: Role of decorin
    Pinki Nandi
    Hyobin Lim
    Eloy Jose Torres-Garcia
    Peeyush K. Lala
    Scientific Reports, 8
  • [50] The Hippo pathway regulates stem cell proliferation, self-renewal, and differentiation
    Liu, Huan
    Jiang, Dandan
    Chi, Fangtao
    Zhao, Bin
    PROTEIN & CELL, 2012, 3 (04) : 291 - 304
12345