Association between fasting and postprandial triglyceride levels and carotid intima-media thickness in type 2 diabetes patients

被引:0
|
作者
陈香
田浩明
刘瑞
机构
[1] Chengdu 610041
[2] China
[3] Department of Endocrinology West China Hospital
[4] Department of Endocrinology and Laboratory of Internal Medicine West China Hospital Sichuan University
关键词
postprandial triglyceride · intima-media thickness · type 2 diabetes mellitus;
D O I
暂无
中图分类号
R587.1 [糖尿病];
学科分类号
1002 ; 100201 ;
摘要
Objective To investigate the association of fasting and postpiandial triglyceride with carotid intima-media thickness among type 2 diabetic patients in southeast China.Methods A total of 78 type 2 diabetic patients from southeast China were recruited. All the subjects underwent a standardized mixed-meal test (SMMT) and an oral glucose tolerance test. Carotid intima-media thickness (IMT) was measured by color doppler ultrasound examination.Results Postprandial triglyceride (PTG) after SMMT increased significantly in type 2 diabetic patients. The carotid IMT in patients with postprandial hypertriglyceridemia was sinificantly greater than that in patients with postprandial normal-triglyceridemia (0.90 mm vs 0.81 mm, P<0.05), which remained significant after adjustment for fasting TG and HDL-c levels, and the IMT in patients with fasting hypertriglyceridemia only had tendency to increase compared to patients with fasting normal-triglyceridemia (0.87 mm vs 0.84 mm, P>0.05). Conclusion The results suggest that postprandial hypertriglyeridemia may be an independent risk factor of early atherosclerosis in type 2 diabetes.
引用
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页码:141 / 143
页数:3
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