Enzymatic Synthesis of Dipeptide Derivatives Containing Non-coded Amino Acids in Organic Solvents

被引:0
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作者
杨洪
周闯
田桂玲
叶蕴华
机构
关键词
thermoase; DEPBT; non-coded amino acid; enzymatic synthesis; peptide;
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暂无
中图分类号
O623 [脂肪族化合物(无环化合物)];
学科分类号
摘要
A series of dipeptide derivatives containing non-coded amino acids, N-Boc-4-X-Phe-Ala-NHNHPh (X=Cl, Br, I, NO 2), were synthesized by using thermoase in organic solvents. The physical data were consistent with the same samples prepared by 3-(diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-one (DEPBT). Influence of different substituted groups of the non-coded amino acids and different organic solvents on the enzymatic peptide synthesis was studied.
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页码:1354 / 1357 +1131
页数:5
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