Programmed cell death and natural killer cells in multiple sclerosis: new potential therapeutic targets?

被引：3
|
作者：
Beatrice Macchi
Antonio Mastino
机构：
[1] Department of Systems Medicine, University of Rome "Tor Vergata"
[2] Department of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina
[3] The Institute of Translational Pharmacology,CNR
来源：
NeuralRegenerationResearch | 2016年 / 11卷 / 05期
关键词：
new potential therapeutic targets; cell; MS;
D O I：
暂无
中图分类号：
R744.51 [];
学科分类号：
1002 ;
摘要：
Multiple sclerosis(MS)is a chronic,severe and complex disease of still uncertain etiopathogenesis,with lesions in the cerebral white matter and spinal cord.The disease is heterogeneous,but is characterized by neuroinflammatory and neurodegenerative processes,usually associated with altered activation of the immune system following presumable stimulation by still unknown autoantigens.Several data confirm that
引用
收藏
页码：733 / 734
页数：2
相关论文
共 50 条
  • [41] Enhancing natural killer cells is beneficial in multiple sclerosis - Commentary
    Segal, Benjamin M.
    MULTIPLE SCLEROSIS JOURNAL, 2019, 25 (04) : 513 - 514
  • [42] Altered invariant natural killer T cells in multiple sclerosis
    Kamel, F.
    Ettorre, A.
    Durrenberger, P. F.
    Malik, O.
    Nicholas, R.
    Boyton, R.
    Altmann, D.
    IMMUNOLOGY, 2011, 135 : 41 - 41
  • [43] A role for natural killer (NK) cells in the immunopathogenesis of multiple sclerosis
    Kastrukoff, LF
    Morgan, N
    Zecchini, D
    Satoh, J
    Paty, D
    NEUROLOGY, 1997, 48 (03) : 1112 - 1112
  • [44] Role of natural killer cells in the pathogenesis and progression of multiple sclerosis
    Morandi, Barbara
    Brarnanti, Placido
    Bonaccorsi, Irene
    Montalto, Erika
    Oliveri, Daniel A.
    Pezzino, Gaetana
    Navarra, Michele
    Ferlazzo, Guido
    PHARMACOLOGICAL RESEARCH, 2008, 57 (01) : 1 - 5
  • [45] Enhancing natural killer cells is beneficial in multiple sclerosis - Yes
    Laroni, Alice
    MULTIPLE SCLEROSIS JOURNAL, 2019, 25 (04) : 510 - 512
  • [46] Natural killer (NK) cells in the immunopathogenesis of multiple sclerosis (MS)
    Kastrukoff, LF
    Lau, AS
    Zecchini, D
    FASEB JOURNAL, 2000, 14 (06): : A1023 - A1023
  • [47] Catching a killer: Mechanisms of programmed cell death and immune activation in Amyotrophic Lateral Sclerosis
    Neel, Dylan, V
    Basu, Himanish
    Gunner, Georgia
    Chiu, Isaac M.
    IMMUNOLOGICAL REVIEWS, 2022, 311 (01) : 130 - 150
  • [48] Investigating the role of natural killer cell subsets in multiple sclerosis
    Harris, A. J.
    Durrenberger, P.
    Kamel, F.
    Ettorre, A.
    Nicholas, R.
    Malik, O.
    Altmann, D. M.
    IMMUNOLOGY, 2010, 131 : 125 - 125
  • [49] Natural sesquiterpene lactones induce programmed cell death in Trypanosoma cruzi: A new therapeutic target?
    Jimenez, V.
    Kemmerling, U.
    Paredes, R.
    Maya, J. D.
    Sosa, M. A.
    Galanti, N.
    PHYTOMEDICINE, 2014, 21 (11) : 1411 - 1418
  • [50] Programmed cell death: molecular mechanisms, biological functions, diseases, and therapeutic targets
    Qian, Shen'er
    Long, Yao
    Tan, Guolin
    Li, Xiaoguang
    Xiang, Bo
    Tao, Yongguang
    Xie, Zuozhong
    Zhang, Xiaowei
    MEDCOMM, 2024, 5 (12):
12345