Challenges and opportunities identifying therapeutic targets for chemotherapy-induced peripheral neuropathy resulting from oxidative DNA damage

被引:0
|
作者
Mark R.Kelley
Jill C.Fehrenbacher
机构
[1] Pediatric Oncology Research
[2] Departments of Biochemistry & Molecular Biology and Pharmacology & Toxicology
[3] HB Wells Center for Pediatric Research
[4] Basic Science Research,Indiana University Simon Cancer Center
[5] Department of Pharmacology and Toxicology
[6] Stark Neuroscience Research Institute
[7] Department of Anesthesiology,Indiana University School of Medicine
基金
美国国家卫生研究院;
关键词
CIPN; DNA; Challenges and opportunities identifying therapeutic targets for chemotherapy-induced peripheral neuropathy resulting from oxidative DNA damage;
D O I
暂无
中图分类号
R745 [周围神经及神经节疾病];
学科分类号
摘要
Background on chemotherapy-induced peripheral neuropathy(CIPN)Incidence,prevalence,and consequences:Up to 90%of cancer patients experience CIPN at some point during or after anticancer treatment(Seretny et al.,2014).Although CIPN is second to hematologic toxicities in regards to the frequency of incidence,
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页码:72 / 74
页数:3
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