Decreased decidual epithelial sodium channel(ENaC) alpha and gamma subunits in recurrent pregnancy loss(RPL)

被引:0
|
作者
Tiantian Yu [1 ]
Chun Feng [2 ]
Pingping Lv [3 ,4 ]
Gufeng Xu [3 ,4 ]
Lihua Hong [3 ,4 ]
Yimeng Xiong [1 ]
Xiaoyan Guo [5 ]
Tong Li [1 ,6 ]
Jianzhong Sheng [3 ,7 ]
Hefeng Huang [1 ,3 ,4 ,6 ]
Xinmei Liu [1 ,6 ]
机构
[1] International Peace Maternal and Child Health Hospital, Shanghai Jiao Tong University, School of Medicine
[2] The Second Affiliated Hospital, School of Medicine, Zhejiang University
[3] Key Laboratory of Reproductive Genetics, Ministry of Education, Zhejiang University
[4] Department of Reproductive Endocrinology, Women's Hospital, School of Medicine, Zhejiang University
[5] Department of Reproductive Endocrinology, Zhejiang Provincial People's Hospital, Hangzhou Medical College
[6] Institute of Embryo-Fetal Original Adult Diseases, School of Medicine, Shanghai Jiao Tong University
[7] Department of Pathology and Pathophysiology, School of Medicine, Zhejiang University
基金
中国国家自然科学基金;
关键词
pro; alpha and gamma subunits in recurrent pregnancy loss; Decreased decidual epithelial sodium channel; RPL;
D O I
暂无
中图分类号
R714.2 [病理妊娠(异常妊娠)];
学科分类号
100211 ;
摘要
Dear Editor,Recurrent pregnancy loss (RPL) in early pregnancy is a devastating problem for couples who want to become parents and a difficult challenge for their physician. RPL is also referred to as recurrent miscarriage or habitual abortion. It is defined as two or more consecutive clinical miscarriages(CMs) before 20 weeks of gestation (Practice Committee of
引用
收藏
页码:988 / 990
页数:3
相关论文
共 50 条
  • [41] Detection of Fully Cleaved Gamma Subunit of the Epithelial Sodium Channel (γ-ENaC) in Kidney Cortex of Healthy and Nephrotic Wild Type Mice
    Omage, Kingsley
    Bohnert, Bernhard
    Worn, Matthias
    Janessa, Andrea
    Artunc, Ferruh
    FASEB JOURNAL, 2021, 35
  • [42] Miscarriage in recurrent pregnancy loss (RPL) patients is associated with decreased peripheral T follicular helper cells and double-positive T cells
    Parvanov, D.
    Jelezarsky, L.
    Ganeva, R.
    Ruseva, M.
    Handzhiyska, M.
    Vidolova, N.
    Metodiev, D.
    Stamenov, G.
    HUMAN REPRODUCTION, 2024, 39 : I377 - I377
  • [43] Common variants of the beta and gamma subunits of the epithelial sodium channel and their relation to plasma renin and aldosterone levels in essential hypertension
    Hannila-Handelberg, T
    Kontula, K
    Tikkanen, I
    Tikkanen, T
    Fyhrquist, F
    Helin, K
    Fodstad, H
    Piippo, K
    Miettinen, HE
    Virtamo, J
    Krusius, T
    Sarna, S
    Gautschi, I
    Schild, L
    Hiltunen, TP
    BMC MEDICAL GENETICS, 2005, 6
  • [44] Role of Nedd4-2 and polyubiquitination in epithelial sodium channel degradation in untransfected renal A6 cells expressing endogenous ENaC subunits
    Malik, B
    Yue, Q
    Yue, G
    Chen, XJ
    Price, SR
    Mitch, WE
    Eaton, DC
    AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2005, 289 (01) : F107 - F116
  • [45] CELL-SPECIFIC EXPRESSION OF EPITHELIAL SODIUM-CHANNEL ALPHA-SUBUNITS, BETA-SUBUNITS, AND GAMMA-SUBUNITS IN ALDOSTERONE-RESPONSIVE EPITHELIA FROM THE RAT - LOCALIZATION BY IN-SITU HYBRIDIZATION AND IMMUNOCYTOCHEMISTRY
    DUC, C
    FARMAN, N
    CANESSA, CM
    BONVALET, JP
    ROSSIER, BC
    JOURNAL OF CELL BIOLOGY, 1994, 127 (06): : 1907 - 1921
  • [46] Increased expression of alpha subunit of epithelial sodium channel (ENaC) and of SGK can account for therapeutic action of glucocorticoids in Meniere's disease
    Marcus, DC
    Pondugula, SR
    Sanneman, JD
    Raveendran, NN
    FASEB JOURNAL, 2004, 18 (05): : A1039 - A1039
  • [47] Identification of epithelial Na plus channel (ENaC) inter-subunit Cl- coordinating residues suggests a trimeric alpha, gamma, beta channel architecture
    Collier, Daniel M.
    Snyder, Peter M.
    FASEB JOURNAL, 2010, 24
  • [48] Molecular analysis of the carboxy terminus of the beta and gamma subunits of the epithelial sodium channel in patients with end-stage renal disease
    Födinger, M
    Schedler, D
    Fritsche-Polanz, R
    Hörl, WH
    Sunder-Plassmann, G
    NEPHRON, 1999, 81 (04) : 381 - 386
  • [49] Increased Cystic Fibrosis Transmembrane Conductance Regulators Expression and Decreased Epithelial Sodium Channel Alpha Subunits Expression in Early Abortion: Findings from a Mouse Model and Clinical Cases of Abortion
    Zhou, Min
    Fu, Jing
    Huang, Wei
    Shen, Licong
    Xiao, Li
    Song, Yong
    Liu, Ying
    PLOS ONE, 2014, 9 (06):
  • [50] Protein Kinase B Alpha (PKBα) Stimulates the Epithelial Sodium Channel (ENaC) Heterologously Expressed in Xenopus laevis Oocytes by Two Distinct Mechanisms
    Diakov, Alexei
    Nesterov, Viatcheslav
    Mokrushina, Marianna
    Rauh, Robert
    Korbmacher, Christoph
    CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2010, 26 (06) : 913 - 924