Rapamycin affect the apoptosis of splenic CD4+ CD25+ regulatory T cells of mouse severe aplastic anemia model

被引:1
|
作者
林赠华 [1 ]
机构
[1] Dept Hematol, Affili Hosp, Nantong Univ
关键词
Rapamycin affect the apoptosis of splenic CD4; regulatory T cells of mouse severe aplastic anemia model;
D O I
暂无
中图分类号
R-332 [医用实验动物学]; R965 [实验药理学];
学科分类号
1001 ; 100602 ; 100706 ;
摘要
Objective To explore the effects and possible mechanism of rapamycin(RAPA)on apoptosis of CD4+CD25+Tregs from the mouse severe aplastic anemia(SAA)model.Methods The BALB/c female SAA model mice were induced by interferon-gamma in combination with busulphan.The SAA model mice were intraperitoneal injection with RAPA at daily dose of 0.5 mg/kg
引用
收藏
页码:117 / 118
页数:2
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