THE ROLE OF ACETYLCHOLINE IN THE RAT BRAIN AND ITS EFFECT ON 5-HYDROXYTRYPTAMINE METABOLISM DURING ELECTROACUPUNCTURE ANALGESIA

被引：0
|
作者：
王友京 [1 ]
伍洁 [1 ]
王双坤 [1 ]
机构：
[1] Institute of Acupuncture Academy of TCM
来源：
JournalofTraditionalChineseMedicine | 1985年 / 04期
关键词：
EAA; THE ROLE OF ACETYLCHOLINE IN THE RAT BRAIN AND ITS EFFECT ON 5-HYDROXYTRYPTAMINE METABOLISM DURING ELECTROACUPUNCTURE ANALGESIA; HT;
D O I：
10.19852/j.cnki.jtcm.1985.04.018
中图分类号：
学科分类号：
摘要：
After electroacupuncture (EA) for 25 minutes stthe bilateral Shousanli (LI 10) and Huantiao (GB30) points of rats,5-hydroxytryptamine (5-HT) con-tents in medulla oblongata plus pons and midbrainmarkedly increased with elevation of pain threshold.However,preliminary intraperitoneal injection of at-ropine,a muscarinic receptor inhibitor of acetylcho-line,not only partially blocked the effect of electroa-cupuncture analgesia (EAA),but also abolished theincrease of 5-HT in the brain.These results suggest that the cholinergic systemmay play an important role in EAA,which may bemediated through the central serotonergic system inthe brain.
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页码：297 / 300
页数：4
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