Identifying therapeutic target genes for diabetic retinopathy using systematic druggable genome-wide Mendelian randomization

被引：0
|
作者：
Long Xie [1 ]
Yu Qin Peng [2 ]
Xiang Shen [1 ]
机构：
[1] The Fourth Hospital of Changsha (Integrated Traditional Chinese and Western Medicine Hospital of Changsha),Department of Orthopedics
[2] Hunan Normal University,Department of Ophthalmology
[3] The Fourth Hospital of Changsha (Integrated Traditional Chinese and Western Medicine Hospital of Changsha),undefined
[4] Hunan Normal University,undefined
来源：
Diabetology & Metabolic Syndrome | / 17卷 / 1期
关键词：
Diabetic retinopathy; Mendelian randomization; GWAS; Druggable target genes;
D O I：
10.1186/s13098-025-01710-y
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] Identifying therapeutic target genes for migraine by systematic druggable genome-wide Mendelian randomization
    Zhang, Chengcheng
    He, Yiwei
    Liu, Lu
    JOURNAL OF HEADACHE AND PAIN, 2024, 25 (01):
  • [2] Systematic druggable genome-wide Mendelian randomization identifies therapeutic targets for sarcopenia
    Yin, Kang-Fu
    Chen, Ting
    Gu, Xiao-Jing
    Su, Wei-Ming
    Jiang, Zheng
    Lu, Si-Jia
    Cao, Bei
    Chi, Li-Yi
    Gao, Xia
    Chen, Yong-Ping
    JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2024, 15 (04) : 1324 - 1334
  • [3] Identification of therapeutic target genes for age-related hearing loss through systematic genome-wide mendelian randomization of druggable genes
    Zhang, Kun
    Hou, Bo
    Yan, Tao
    Qiao, Ruru
    Qu, Peng
    Xu, Xinbo
    Zhang, Hanbing
    EXPERIMENTAL GERONTOLOGY, 2025, 200
  • [4] Identifying therapeutic targets for ovarian cancer: a druggable genome-wide Mendelian randomization study
    Chen, Siyu
    Zheng, Min
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2024, 34 (SUPPL_3) : A206 - A206
  • [5] Systematic druggable genome-wide Mendelian randomization identifies therapeutic targets for hyperemesis gravidarum
    Wang, Fengyang
    Ruan, Wenpeng
    Yin, Qiuyuan
    Zhu, Lei
    BMC PREGNANCY AND CHILDBIRTH, 2024, 24 (01)
  • [6] Systematic druggable genome-wide Mendelian randomization identifies therapeutic targets for lung cancer
    Song, Wenfu
    Li, Yingying
    Yao, Yaxuan
    Sun, Shiling
    Guan, Xutao
    Wang, Bing
    BMC CANCER, 2024, 24 (01)
  • [7] Based on systematic druggable genome-wide Mendelian randomization identifies therapeutic targets for diabetes
    Li, Hu
    Li, Wei
    Li, Dongyang
    Yuan, Lijuan
    Xu, Yucheng
    Su, Pengtao
    Wu, Liqiang
    Zhang, Zhiqiang
    FRONTIERS IN ENDOCRINOLOGY, 2024, 15
  • [8] Systematic druggable genome-wide Mendelian randomization to identify therapeutic targets and dominant flora for ulcerative colitis
    Ou, Haiya
    Huang, Hongshu
    Xu, Yiqi
    Lin, Haixiong
    Wang, Xiaotong
    PHARMACOLOGICAL RESEARCH, 2025, 213
  • [9] Druggable genome-wide Mendelian randomization for identifying the role of integrated stress response in therapeutic targets of bipolar disorder
    Zhai, Ting
    JOURNAL OF AFFECTIVE DISORDERS, 2024, 362 : 843 - 852
  • [10] Comprehensive Druggable Genome-Wide Mendelian Randomization Reveals Therapeutic Targets for Kidney Diseases
    Su Zhihang
    Xue Rui
    Wan Qijun
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2024, 35 (10):
12345