Catalyst- and solvent-free hydrosulfonylation of alkenes with sulfinates enabling green synthesis of β-sulfonyl amides

被引：0

作者：

Luo, Dan ^{[1
]}

Wang, Qian ^{[1
]}

Mei, Haibo ^{[1
]}

Han, Jianlin ^{[1
]}

机构：

[1] Nanjing Forestry Univ, Coll Chem Engn, Jiangsu Coinnovat Ctr Efficient Proc & Utilizat Fo, Nanjing 210037, Peoples R China

来源：

TETRAHEDRON | 2025年 / 179卷

基金：

中国国家自然科学基金;

关键词：

Hydrosulfonylation reaction; Solvent-free; Sodium sulfinates; beta-sulfonyl amides; Alkenes;

D O I：

10.1016/j.tet.2025.134632

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient hydrosulfonylation reaction of alkenes with sodium sulfinates as Michael donors has been developed, which affords (3-sulfonyl amides as products with up to 99 % yield. This reaction was conducted under mild conditions without the need of any catalyst, in particular, no solvent was needed for this transformation. This reaction represents the first example of hydrosulfonylation reaction with sodium sulfinates under neat conditions. Moreover, this reaction features wide range of structurally diverse alkenes and sodium sulfinates, which provides a green and valuable strategy for the synthesis of (3-sulfonyl amides.

引用

页数：8

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