Downregulation of PD-L1 expression by Wnt pathway inhibition to enhance PD-1 blockade efficacy in hepatocellular carcinoma

被引:0
|
作者
Yu-Yun Shao [1 ]
Han-Yu Wang [3 ]
Hung-Wei Hsu [4 ]
Rita Robin Wo [3 ]
Ann-Lii Cheng [3 ]
Chih-Hung Hsu [3 ]
机构
[1] National Taiwan University College of Medicine,Graduate Institute of Oncology
[2] National Taiwan University College of Medicine,Department of Internal Medicine
[3] National Taiwan University Hospital,Department of Oncology
[4] National Taiwan University Cancer Center,Department of Medical Oncology
关键词
Beta-catenin; Hepatocellular carcinoma; Immunotherapy; Programmed death-ligand 1; Tankyrase; Wnt pathway;
D O I
10.1186/s13062-025-00645-8
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