Blocking Intracellular TXNIP Shuttling Attenuates Reactive Oxygen Species-Associated NLRP3 Inflammasome Activation Induced by Tubulointerstitial Fibrosis in Diabetic Kidney Disease

被引:0
|
作者
Wang Li [1 ]
Zhu Bingbing [1 ]
Liu Shuang [1 ]
Xingmei Yao [1 ]
Zhou Yuying [1 ]
机构
[1] Shanghai Univ Tradit Chinese Med, Putuo Hosp, Dept Nephrol, Shanghai, Peoples R China
来源
关键词
D O I
10.1681/ASN.2024evbkm13m
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
SA-PO256
引用
收藏
页数:2
相关论文
共 50 条
  • [41] Peroxyauraptenol Inhibits Inflammation and NLRP3 Inflammasome Activation by Inhibiting Reactive Oxygen Species Generation and Preserving Mitochondrial Integrity
    Chao, Louis Kuoping
    Lin, Cheng-Hsiu
    Chiu, Huan-Wen
    Wong, Wei-Ting
    Chiu, Hsiao-Wen
    Tasi, Yu-Ling
    Kuo, Yueh-Hsiung
    Chiu, Yi-Chich
    Liu, May-Lan
    Ho, Chen-Lung
    Hua, Kuo-Feng
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2015, 63 (04) : 1210 - 1219
  • [42] Urolithin A suppresses NLRP3 inflammasome activation by inhibiting the generation of reactive oxygen species and prevents monosodium urate crystal-induced peritonitis
    Komatsu, Wataru
    Kishi, Hisashi
    Uchiyama, Koji
    Ohhira, Shuji
    Kobashi, Gen
    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2024, 88 (08) : 966 - 978
  • [43] Mitochondrial NLRP3 Protein Induces Reactive Oxygen Species to Promote Smad Protein Signaling and Fibrosis Independent from the Inflammasome
    Bracey, Nathan A.
    Gershkovich, Benjamin
    Chun, Justin
    Vilaysane, Akosua
    Meijndert, H. Christopher
    Wright, James R., Jr.
    Fedak, Paul W.
    Beck, Paul L.
    Muruve, Daniel A.
    Duff, Henry J.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2014, 289 (28) : 19571 - 19584
  • [44] Mitochondrial reactive oxygen species-mediated NLRP3 inflammasome activation contributes to aldosterone-induced renal tubular cells injury
    Ding, Wei
    Guo, Honglei
    Xu, Chengyan
    Wang, Bin
    Zhang, Minmin
    Ding, Feng
    ONCOTARGET, 2016, 7 (14) : 17479 - 17491
  • [45] Melatonin inhibits endoplasmic reticulum stress-associated TXNIP/NLRP3 inflammasome activation in lipopolysaccharide-induced endometritis in mice
    Hu, Xiaoyu
    Li, Depeng
    Wang, Jiaxin
    Guo, Jian
    Li, Yanyi
    Cao, Yongguo
    Zhang, Naisheng
    Fu, Yunhe
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2018, 64 : 101 - 109
  • [46] Suramin prevents the development of diabetic kidney disease by inhibiting NLRP3 inflammasome activation in KK-Ay mice
    Oda, Kaori
    Miyamoto, Satoshi
    Kodera, Ryo
    Wada, Jun
    Shikata, Kenichi
    JOURNAL OF DIABETES INVESTIGATION, 2023, 14 (02) : 205 - 220
  • [47] PROPHYLACTIC nCMT-3 ATTENUATES SEPSIS-INDUCED ACUTE KIDNEY INJURY IN ASSOCIATION WITH NLRP3 INFLAMMASOME ACTIVATION AND APOPTOSIS
    Ma, Julia
    Wang, Xiaojing
    Gu, Raymond
    Guo, Dandan
    Shi, Changying
    Kollisch-Singule, Michaela
    Suo, Liye
    Luo, Juntao
    Meng, Qinghe
    Cooney, Robert N.
    SHOCK, 2023, 59 (06): : 922 - 929
  • [48] Ruscogenin Attenuates Cerebral Ischemia-Induced Blood-Brain Barrier Dysfunction by Suppressing TXNIP/NLRP3 Inflammasome Activation and the MAPK Pathway
    Cao, Guosheng
    Jiang, Nan
    Hu, Yang
    Zhang, Yuanyuan
    Wang, Guangyun
    Yin, Mingzhu
    Ma, Xiaonan
    Zhou, Kecheng
    Qi, Jin
    Yu, Boyang
    Kou, Junping
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2016, 17 (09)
  • [49] Disulfiram attenuates lipopolysaccharide-induced acute kidney injury by suppressing oxidative stress and NLRP3 inflammasome activation in mice
    Huang, Jie
    Wei, Shanshan
    Peng, Zhenyu
    Xiao, Zijun
    Yang, Yuanying
    Liu, Jiaqin
    Zhang, Bikui
    Li, Wenqun
    JOURNAL OF PHARMACY AND PHARMACOLOGY, 2022, 74 (02) : 259 - 267
  • [50] Isomaculosidine facilitates NLRP3 inflammasome activation by promoting mitochondrial reactive oxygen species production and causes idiosyncratic liver injury
    Shi, Wei
    Liu, Tingting
    Yang, Huijie
    Zhao, Jia
    Wei, Ziying
    Huang, Yujiao
    Li, Zhiyong
    Li, Hui
    Liang, Longxin
    Hou, Xiaorong
    Chen, Yuanyuan
    Gao, Yuan
    Bai, Zhaofang
    Xiao, Xiaohe
    JOURNAL OF ETHNOPHARMACOLOGY, 2024, 319