Nanobody mediated Central nervous system-targeted complement inhibition mediates neuroprotection in a murine model of progressive multiple sclerosis

被引：0
|
作者：
Pike, Steven [1 ]
Linzey, Michael [1 ]
Tran, Hiep [2 ]
DeCristofano, Laura [2 ]
Phillips, Andrew [2 ]
Gilli, Francesca [1 ]
机构：
[1] Dartmouth Hitchcock Med Ctr, Neurol, Lebanon, NH USA
[2] Abzyme Therapeut LLC, Pottstown, PA USA
来源：
MULTIPLE SCLEROSIS JOURNAL | 2024年 / 30卷 / 03期
关键词：
D O I：
暂无
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
P800/2381
引用
收藏
页码：614 / 614
页数：1
相关论文
共 50 条
  • [31] Metabolomics of cerebrospinal fluid reveals changes in the central nervous system metabolism in a rat model of multiple sclerosis
    Marek J. Noga
    Adrie Dane
    Shanna Shi
    Amos Attali
    Hans van Aken
    Ernst Suidgeest
    Tinka Tuinstra
    Bas Muilwijk
    Leon Coulier
    Theo Luider
    Theo H. Reijmers
    Rob J. Vreeken
    Thomas Hankemeier
    Metabolomics, 2012, 8 : 253 - 263
  • [32] Transient Peripheral Immune Response and Central Nervous System Leaky Compartmentalization in a Viral Model for Multiple Sclerosis
    Navarrete-Talloni, Maria Jose
    Kalkuhl, Arno
    Deschl, Ulrich
    Ulrich, Reiner
    Kummerfeld, Maren
    Rohn, Karl
    Baumgaertner, Wolfgang
    Beineke, Andreas
    BRAIN PATHOLOGY, 2010, 20 (05) : 890 - 901
  • [33] Metabolomics of cerebrospinal fluid reveals changes in the central nervous system metabolism in a rat model of multiple sclerosis
    Noga, Marek J.
    Dane, Adrie
    Shi, Shanna
    Attali, Amos
    van Aken, Hans
    Suidgeest, Ernst
    Tuinstra, Tinka
    Muilwijk, Bas
    Coulier, Leon
    Luider, Theo
    Reijmers, Theo H.
    Vreeken, Rob J.
    Hankemeier, Thomas
    METABOLOMICS, 2012, 8 (02) : 253 - 263
  • [34] Peripheral blood gene expression signature mirrors central nervous system disease: The model of multiple sclerosis
    Achiron, A.
    Gurevich, M.
    AUTOIMMUNITY REVIEWS, 2006, 5 (08) : 517 - 522
  • [35] MicroRNA signature of central nervous system-infiltrating dendritic cells in an animal model of multiple sclerosis
    Hoye, Mariah L.
    Archambault, Angela S.
    Gordon, Taylor M.
    Oetjen, Landon K.
    Cain, Matthew D.
    Klein, Robyn S.
    Crosby, Seth D.
    Kim, Brian S.
    Miller, Timothy M.
    Wu, Gregory F.
    IMMUNOLOGY, 2018, 155 (01) : 112 - 122
  • [36] NEUROGENIC BLADDER DYSFUNCTION IN A MURINE MODEL OF MULTIPLE SCLEROSIS IS CAUSED BY CORONOVIRUS-INDUCED DEMYELINATION OF THE NERVOUS SYSTEM
    Ruggieri, Michael
    McMillan, Matthew
    Pan, Xiao-Qing
    Lamarre, Neil
    Braverman, Alan
    Jindal, Manila
    O'Donnell, Cullen
    Newman, Diane
    Smith, Ariana
    Malykhina, Anna
    JOURNAL OF UROLOGY, 2014, 191 (04): : E138 - E138
  • [37] KATP channel opener NT-KO-003 mediates neuroprotection by a novel mechanism of action and induces beneficial effects in a murine model of multiple sclerosis
    Virgili, N.
    Mancera, P.
    Pasten-Zamorano, A.
    Wappenhans, B.
    Sorrosal, G.
    De Frias, M.
    Campas, C.
    Bustos, J.
    Pugliese, M.
    Espinosa-Parrilla, J. F.
    MULTIPLE SCLEROSIS JOURNAL, 2012, 18 : 442 - 442
  • [38] Central Nervous System Proteomics in Animal Model of Multiple Sclerosis Revealed Down-Regulation of Mithochondrial Proteins
    Fazeli, Abolhassan Shahzadeh
    Sanati, Mohammad Hossein
    Nasrabadi, Davood
    Pouya, Alireza
    Baharvand, Hossein
    Salekdeh, Ghasem Hosseini
    YAKHTEH, 2009, 11 (02): : 236 - 243
  • [39] SPONTANEOUS AND INDUCED REMYELINATION IN MULTIPLE-SCLEROSIS AND THE THEILERS VIRUS MODEL OF CENTRAL-NERVOUS-SYSTEM DEMYELINATION
    MILLER, DJ
    RODRIGUEZ, M
    MICROSCOPY RESEARCH AND TECHNIQUE, 1995, 32 (03) : 230 - 245
  • [40] MONOCLONAL AUTOANTIBODIES PROMOTE CENTRAL-NERVOUS-SYSTEM REPAIR IN AN ANIMAL-MODEL OF MULTIPLE-SCLEROSIS
    MILLER, DJ
    SANBORN, KS
    KATZMANN, JA
    RODRIGUEZ, M
    JOURNAL OF NEUROSCIENCE, 1994, 14 (10): : 6230 - 6238
12345