STAT3 is associated with differential responses to pembrolizumab through IFN-γ-induced apoptosis in urothelial cancer

被引：0
|
作者：
Ando, Kiyohiro [1 ]
Fuchizawa, Hirotaka [2 ]
Motoi, Noriko [3 ]
Iizuka, Toshihiko [3 ]
Inoue, Masaharu [2 ]
Mitani, Koki [2 ]
Sano, Yuta [2 ]
Takenobu, Hisanori [1 ]
Haruta, Masayuki [1 ]
Onuki, Ritsuko [1 ]
Matsuoka, Yoh [2 ]
Kanda, Hiroaki [3 ]
Kamijo, Takehiko [1 ]
Kageyama, Yukio [3 ]
机构：
[1] Saitama Canc Ctr, Res Inst Clin Oncol, Ina, Saitama, Japan
[2] Saitama Canc Ctr, Dept Urol, Ina, Saitama, Japan
[3] Saitama Canc Ctr, Dept Pathol, Ina, Saitama, Japan
来源：
CANCER SCIENCE | 2025年 / 116卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
P-3245
引用
收藏
页码：1705 / 1705
页数：1
相关论文
共 50 条
  • [21] STAT3/p53 pathway activation disrupts IFN-β-induced dormancy in tumor-repopulating cells
    Liu, Yuying
    Lv, Jiadi
    Liu, Jinyan
    Liang, Xiaoyu
    Jin, Xun
    Xie, Jing
    Zhang, Le
    Chen, Degao
    Fiskesund, Roland
    Tang, Ke
    Ma, Jingwei
    Zhang, Huafeng
    Dong, Wenqian
    Mo, Siqi
    Zhang, Tianzhen
    Cheng, Feiran
    Zhou, Yabo
    Jia, Qingzhu
    Zhu, Bo
    Kong, Yan
    Guo, Jun
    Zhang, Haizeng
    Hu, Zhuo-Wei
    Cao, Xuetao
    Qin, F. Xiao-Feng
    Huang, Bo
    JOURNAL OF CLINICAL INVESTIGATION, 2018, 128 (03): : 1057 - 1073
  • [22] Contribution of STAT3 on the resistance of cervical cancer against TRAIL-induced apoptosis
    Nakamura, Hiroe
    Kawana, Kei
    Taguchi, Ayumi
    Yoshida, Mitsuyo
    Satoh, Masakazu
    Fujimoto, Asaha
    Adachi, Katsuyuki
    Koga, Kaori
    Oda, Katsutoshi
    Osuga, Yutaka
    Fujii, Tomoyuki
    JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 2015, 112 : 136 - 137
  • [23] Differential roles of STAT3 depending on the mechanism of STAT3 activation in gastric cancer cells.
    Okamoto, Wataru
    Okamoto, Isamu
    Tuchihara, Katsuya
    Yanagihara, Kazuyoshi
    Nishio, Kazuto
    Nakagawa, Kazuhiko
    MOLECULAR CANCER THERAPEUTICS, 2013, 12 (11)
  • [24] STAT3/p53 pathway activation disrupts IFN-β-induced dormancy in tumor-repopulating cells
    Lv, J.
    Huang, B.
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2019, 49 : 170 - 170
  • [25] Pretreatment of LPS inhibits IFN-β-induced STAT1 phosphorylation through SOCS3 induced by LPS
    Ando, Takashi
    Komatsu, Takayuki
    Naiki, Yoshikazu
    Yokochi, Takashi
    Watanabe, Daisuke
    Koide, Naoki
    BIOMEDICINE & PHARMACOTHERAPY, 2015, 76 : 1 - 5
  • [26] Survivin suppression through STAT3/β-catenin is essential for resveratrol-induced melanoma apoptosis
    Habibie
    Yokoyama, Satoru
    Abdelhamed, Sherif
    Awale, Suresh
    Sakurai, Hiroaki
    Hayakawa, Yoshihiro
    Saiki, Ikuo
    INTERNATIONAL JOURNAL OF ONCOLOGY, 2014, 45 (02) : 895 - 901
  • [27] IFN-α induces the human IL-10 gene by recruiting both IFN regulatory factor 1 and Stat3
    Ziegler-Heitbrock, L
    Lötzerich, M
    Schaefer, A
    Werner, T
    Frankenberger, M
    Benkhart, E
    JOURNAL OF IMMUNOLOGY, 2003, 171 (01): : 285 - 290
  • [28] Systemic Interferon-α (IFN-α) Treatment Leads to Stat3 Inactivation in Melanoma Precursor Lesions
    John M. Kirkwood
    Daniel L. Farkas
    Arup Chakraborty
    Kevin F. Dyer
    David J. Tweardy
    John L. Abernethy
    Howard D. Edington
    Sandra S. Donnelly
    Dorothea Becker
    Molecular Medicine, 1999, 5 : 11 - 20
  • [29] Systemic interferon-α (IFN-α) treatment leads to Stat3 inactivation in melanoma precursor lesions
    Kirkwood, JM
    Farkas, DL
    Chakraborty, A
    Dyer, KF
    Tweardy, DJ
    Abernethy, JL
    Edington, HD
    Donnelly, SS
    Becker, D
    MOLECULAR MEDICINE, 1999, 5 (01) : 11 - 20
  • [30] Immunohistochemical evaluation of Stat3 signaling and apoptosis in oral cancer
    Toutouzas, I.
    Nikitakis, N.
    Chrysomali, E.
    Sklavounou, A.
    ORAL DISEASES, 2012, 18 : 3 - 3
12345