STAT3 is associated with differential responses to pembrolizumab through IFN-γ-induced apoptosis in urothelial cancer

被引：0
|
作者：
Ando, Kiyohiro [1 ]
Fuchizawa, Hirotaka [2 ]
Motoi, Noriko [3 ]
Iizuka, Toshihiko [3 ]
Inoue, Masaharu [2 ]
Mitani, Koki [2 ]
Sano, Yuta [2 ]
Takenobu, Hisanori [1 ]
Haruta, Masayuki [1 ]
Onuki, Ritsuko [1 ]
Matsuoka, Yoh [2 ]
Kanda, Hiroaki [3 ]
Kamijo, Takehiko [1 ]
Kageyama, Yukio [3 ]
机构：
[1] Saitama Canc Ctr, Res Inst Clin Oncol, Ina, Saitama, Japan
[2] Saitama Canc Ctr, Dept Urol, Ina, Saitama, Japan
[3] Saitama Canc Ctr, Dept Pathol, Ina, Saitama, Japan
来源：
CANCER SCIENCE | 2025年 / 116卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
P-3245
引用
收藏
页码：1705 / 1705
页数：1
相关论文
共 50 条
  • [1] STAT3 Contributes a Favorable Response to Pembrolizumab Through IFN-γ-induced Apoptosis in Urothelial Cancer
    Fuchizawa, Hirotaka
    Ando, Kiyohiro
    Motoi, Noriko
    Iizuka, Toshihiko
    Inoue, Masaharu
    Mitani, Kouki
    Sano, Yuta
    Takenobu, Hisanori
    Haruta, Masayuki
    Onuki, Ritsuko
    Matsuoka, Yoh
    Kamijo, Takehiko
    Kageyama, Yukio
    ANTICANCER RESEARCH, 2024, 44 (05) : 1925 - 1930
  • [2] A novel anti-viral role for STAT3 in IFN-α signalling responses
    Rebecca Mahony
    Siobhán Gargan
    Kim L. Roberts
    Nollaig Bourke
    Sinead E. Keating
    Andrew G. Bowie
    Cliona O’Farrelly
    Nigel J. Stevenson
    Cellular and Molecular Life Sciences, 2017, 74 : 1755 - 1764
  • [3] A novel anti-viral role for STAT3 in IFN-α signalling responses
    Mahony, Rebecca
    Gargan, Siobhan
    Roberts, Kim L.
    Bourke, Nollaig
    Keating, Sinead E.
    Bowie, Andrew G.
    O'Farrelly, Cliona
    Stevenson, Nigel J.
    CELLULAR AND MOLECULAR LIFE SCIENCES, 2017, 74 (09) : 1755 - 1764
  • [4] Cutting edge:: Role of STAT1, STAT3, and STAT5 IFN-αβ responses in T lymphocytes
    Tanabe, Y
    Nishibori, T
    Su, L
    Arduini, RM
    Baker, DP
    David, M
    JOURNAL OF IMMUNOLOGY, 2005, 174 (02): : 609 - 613
  • [5] Involvement of STAT3 in IL-6 and IFN-γ induced enteric apelin expression
    Ha, Song
    Wang, Guiyun
    Qi, Xiang
    Greeley, George H.
    GASTROENTEROLOGY, 2008, 134 (04) : A392 - A392
  • [6] STAT3 and apoptosis challenges in cancer
    Fathi, Nazanin
    Rashidi, Golnaz
    Khodadadi, Ali
    Shahi, Shahriar
    Sharifi, Simin
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 117 : 993 - 1001
  • [7] STAT3 is a negative regulator of type I IFN-induced antiviral responses
    Wang, Wei-Bei
    Lee, Chien-Kuo
    CYTOKINE, 2008, 43 (03) : 266 - 267
  • [8] Resistance to IFN-α-Induced Apoptosis Is Linked to a Loss of STAT2
    Romero-Weaver, Ana L.
    Wang, Hsiang-Wen
    Steen, Hakan C.
    Scarzello, Anthony J.
    Hall, Veronica L.
    Sheikh, Faruk
    Donnelly, Raymond P.
    Gamero, Ana M.
    MOLECULAR CANCER RESEARCH, 2010, 8 (01) : 80 - 92
  • [9] ACSM3 Suppresses Ovarian Cancer Progression by Inactivating the IFN-γ/JAK/STAT3 Signaling Pathway
    Wang, Juan
    Sun, Yanqiu
    Wu, Ruixue
    ADVANCED BIOLOGY, 2025, 9 (03):
  • [10] STAT3 polymorphism: a potential marker of response to IFN-α therapy in metastatic RCC
    Nature Clinical Practice Oncology, 2007, 4 (10): : 561 - 561
12345