Clinical Practice Guidelines for the Management of Congenital Syphilis in Japan, 2023: Executive Summary

被引：0

作者：

Ito, Yoshinori ^{[1
]}

Yamagishi, Takuya ^{[2
]}

Ikenoue, Chiaki ^{[1
]}

Ishiwada, Naruhiko ^{[1
]}

Ito, Kenta ^{[1
]}

Iwatani, Sota ^{[3
]}

Ouchi, Kazunobu ^{[1
]}

Kawana, Kei ^{[4
]}

Shimizu, Hiroyuki ^{[1
]}

Shinjoh, Masayoshi ^{[1
]}

Takeuchi, Noriko ^{[1
]}

Tsugawa, Takeshi ^{[1
]}

Funaki, Takanori ^{[1
]}

Furuichi, Munehiro ^{[1
]}

Hoshino, Tadashi ^{[1
]}

Mikamo, Hiroshige ^{[2
]}

Miyairi, Isao ^{[1
]}

Moriuchi, Hiroyuki ^{[1
]}

Morioka, Ichiro ^{[3
]}

Yamagishi, Yuka ^{[1
]}

Mori, Masaaki ^{[1
]}

机构：

[1] Japanese Soc Pediat Infect Dis, Tokyo, Japan

[2] Japanese Soc Sexually Transmitted Infect, Tokyo, Japan

[3] Japan Soc Neonatal Hlth & Dev, Tokyo, Japan

[4] Japan Soc Infect Dis Obstet & Gynecol, Tokyo, Japan

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2025年 / 44卷 / 03期

关键词：

guideline; syphilis; congenital syphilis; Japan; AMOXICILLIN; CEFTRIAXONE; PENICILLIN;

D O I：

10.1097/INF.0000000000004665

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Congenital syphilis (CS) is a mother-to-child infection caused by the bacterium Treponema pallidum, transmitted through the placenta. In Japan, the number of syphilis cases has recently increased, accompanied by an increase in CS cases. Thus, automated methods for serum antibodies with serial values, without a 2x dilution sequence, have been widely used. Moreover, benzathine penicillin G was introduced in Japan in 2021. In response to the recent surge in CS, the first edition of the clinical practice guidelines for the management of CS was developed by a committee comprising representatives from 4 Japanese medical societies. This summary outlines 5 clinical questions with statements and expert comments regarding diagnosis, treatment and follow-up requirements. These guidelines aim to assist in the management of patients with CS infection.

引用

页码：e90 / e94

页数：5

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