Activation-Inducible Bispecific BCMA-CD24 CAR-T Cells Precisely and Safely Control Multiple Myeloma Growth

被引：0
|
作者：
Sun, Fumou [1 ]
Dong, Jing [1 ]
Hematti, Peiman [2 ]
Janz, Siegfried [2 ]
Dhakal, Binod [3 ]
机构：
[1] Med Coll Wisconsin, Dept Med, Milwaukee, WI USA
[2] Med Coll Wisconsin, Dept Med, Div Hematol & Oncol, Milwaukee, WI USA
[3] Med Coll Wisconsin, Milwaukee, WI USA
来源：
BLOOD | 2024年 / 144卷
关键词：
D O I：
10.1182/blood-2024-205476
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：4791 / 4792
页数：2
相关论文
共 50 条
  • [21] BCMA/CD47-directed universal CAR-T cells exhibit excellent antitumor activity in multiple myeloma
    Lu, Qizhong
    Li, Hexian
    Wu, Zhiguo
    Zhu, Zhixiong
    Zhang, Zongliang
    Yang, Donghui
    Tong, Aiping
    JOURNAL OF NANOBIOTECHNOLOGY, 2024, 22 (01)
  • [22] High Activation of BCMA CAR-T Cells Contributes to Increased Response Rate for Patients With Relapsed/Refractory Multiple Myeloma
    Hu, Yongxian
    Zhao, Houli
    Chang, Alex Hongsheng
    Nagler, Arnon
    Huang, He
    BONE MARROW TRANSPLANTATION, 2020, 55 (SUPPL 1) : 51 - 51
  • [23] Early Dynamics and Depth of Response in Multiple Myeloma Patients Treated With BCMA CAR-T Cells
    Wong, Sandy W.
    Shah, Nina
    Ledergor, Guy
    Martin, Thomas
    Wolf, Jeffrey
    Shui, Amy M.
    Huang, Chiung-Yu
    Martinez-Lopez, Joaquin
    FRONTIERS IN ONCOLOGY, 2021, 11
  • [24] Monitoring of Anti-BCMA CAR-T Cells and non-CAR-T Immune Subsets in Multiple Myeloma Patients
    Venglar, Ondrej
    Viera, Hrabcakova
    Soucek, Ondrej
    Kutejova, Kamila
    Mihalyova, Jana
    Muronova, Ludmila
    Popkova, Tereza
    Zihala, David
    Sevcikova, Tereza
    Broskevicova, Lucie
    Hajek, Roman
    Folber, Frantisek
    Radocha, Jakub
    Jelinek, Tomas
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2024, 24 : S95 - S95
  • [25] Antibody-drug conjugates, bispecific antibodies and CAR-T cells therapy in multiple myeloma
    Tacchetti, Paola
    Talarico, Marco
    Barbato, Simona
    Pantani, Lucia
    Mancuso, Katia
    Rizzello, Ilaria
    Zamagni, Elena
    Cavo, Michele
    EXPERT REVIEW OF ANTICANCER THERAPY, 2024, 24 (06) : 379 - 395
  • [26] Timing and Nature of Infections in Multiple Myeloma Patients Treated with Anti-BCMA CAR-T Cells
    Lancman, Guido
    Shyu, Margaret
    Metzger, Megan
    Parsa, Kian
    Cho, Hearn J.
    Parekh, Samir
    Richter, Joshua
    Rodriguez, Cesar
    Rossi, Adriana
    Sanchez, Larysa
    Thibaud, Santiago
    Jagannath, Sundar
    Chari, Ajai
    Richard, Shambavi
    BLOOD, 2022, 140 : 7198 - 7199
  • [27] Canadian-made single domain antibody (sdAb) BCMA CAR-T cells for multiple myeloma
    Lindo, Lorenzo
    Waller, Daniel
    Wilkinson, Lauren
    Selleri, Silvia
    Arbabi-Ghahroudi, Mehdi
    McComb, Scott
    Bergsagel, Leif
    Chesi, Marta
    Hay, Kevin
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2023, 23 : S48 - S49
  • [28] Clinical Outcomes of BCMA CAR-T Cells in a Multiple Myeloma Patient With Central Nervous System Invasion
    Wang, Ting
    He, Ting
    Ma, Lie
    Yang, Yazi
    Feng, Ru
    Ding, Yanping
    Shan, Yueming
    Bu, Bing
    Qi, Feifei
    Wu, Fei
    Lu, Xin-an
    Liu, Hui
    FRONTIERS IN ONCOLOGY, 2022, 12
  • [29] Preclinical evaluation of CD8+Anti-BCMA mRNA CAR T-Cells for control of multiple myeloma
    Lin, Liang
    Xing, Lijie
    Cho, Shih-Feng
    Wen, Kenneth
    Hsieh, Phillip
    Kurtoglu, Metin
    Zhang, Yi
    Stewart, C. Andrew
    Anderson, Kenneth C.
    Tai, Yu-Tzu
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2019, 19 (10): : E169 - E169
  • [30] Single VHH-directed BCMA CAR-T cells cause remission of relapsed/refractory multiple myeloma
    Lu Han
    Ji-Shuai Zhang
    Jian Zhou
    Ke-Shu Zhou
    Ben-Ling Xu
    Lin-Lin Li
    Bai-Jun Fang
    Qing-Song Yin
    Xing-Hu Zhu
    Hu Zhou
    Xu-Dong Wei
    Hong-Chang Su
    Bing-Xiang Zhang
    Ya-Nan Wang
    Bin Xiang
    Quan-Li Gao
    Yong-Ping Song
    Leukemia, 2021, 35 : 3002 - 3006
12345