At the European Space Astronomy Centre (ESAC) near Madrid, the ESAC Science Data Centre (ESDC) hosts ESA archives for Astronomy, Planetary and Heliophysics Space Science. Furthermore, the GNSS Science Support Centre (GSSC), with special attention to Galileo and EGNOS, consolidates an ESA archive for scientific exploitation of Global Navigation Satellite Systems (GNSS). The sheer amount of data derived from current development plans for Space Science and Navigation Systems, constitutes a unique opportunity for research. Nevertheless, this deluge of data triggers a depart from standard processes and architectures supporting archives exploitation. More than ever, science innovation requires to integrate multiple data sources, sophisticated computing algorithms and cross-domain collaboration system to achieve its goals. Hence, motivated by this increasingly complex landscape, 'ESA Datalabs' and 'GSSC Now' platforms expand Space and Navigation Science archives respectively, with a brand-new palette of collaboration, exploration, and analysis capabilities. Designed from the ground-up with a focus on end-user productivity, these platforms accelerate time to market for science operations developments and increase their return on investment, unleashing the full potential of ESA Missions archives. Transparently to the user, the two platforms implement advanced network and computing capabilities to leave behind the discovery and download science era. This work presents ESA vision and initiatives to provide a multi-mission environment for Science Data Exploitation, centered on the transformative concept of relocating processing components to the data, rather than transferring vast datasets to the users.