Barriers and facilitators of the application of precision medicine to the genitourinary cancer care pathway: Perspective from a low- and middle-income country in sub-Saharan Africa

被引:0
|
作者
Tolani, Musliu Adetola [1 ,2 ]
Zubairu, Ismail Hadi [1 ,3 ]
Balarabe, Kabir [1 ,4 ]
Awaisu, Mudi [1 ,2 ]
Abdullahi, Mubarak [1 ,5 ]
Adeniji, Adeoluwa Akeem [6 ]
Umar, Shehu Salihu [1 ,3 ]
Bello, Ahmad [1 ,2 ]
Tagawa, Scott T. [7 ]
机构
[1] Ahmadu Bello Univ, Coll Med, Zaria, Nigeria
[2] Ahmadu Bello Univ, Dept Surg, Div Urol, Teaching Hosp, Zaria, Nigeria
[3] Ahmadu Bello Univ, Honourable Mukhtar Aliyu Betara Ctr Excellence Onc, Teaching Hosp, Zaria, Nigeria
[4] Ahmadu Bello Univ, Teaching Hosp, Dept Pathol, Zaria, Nigeria
[5] Ahmadu Bello Univ, Teaching Hosp, Dept Radiol, Zaria, Nigeria
[6] MeCure Canc Ctr, Lagos, Nigeria
[7] Weill Cornell Med, Div Hematol & Med Oncol, New York, NY USA
关键词
Biomarker; Bladder cancer; Clinical trial; Nigeria; Precision medicine; Prostate cancer; Renal cancer; PROSTATE; UTILITY; BLADDER;
D O I
10.1016/j.urolonc.2024.07.014
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The benefit of the delivery of the right form of cancer care, tailored to the right patient, at the right time is increasingly being recognized in the global oncology community. Information on the role and feasible potential of precision oncology during the management of genitourinary cancer in Nigeria, the most populous country in Africa, is limited. This article, therefore, describes the present application of personalized medicine in Nigeria and its barriers and facilitators. It provided granular details on manpower distribution and epidemiological disparities. It also explored the use of clinical and biological markers for screening and early diagnosis, the application of team science to support genomic profiling, cost-effective approaches for image-based phenotypic precision oncology, the emerging role of molecular imaging, access to clinical trials; and their potential to support data driven diagnosis, treatment decision and care availability in order to address gaps in genitourinary cancer management in the country. (c) 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.
引用
收藏
页码:411 / 420
页数:10
相关论文
共 50 条
  • [31] COVID-19 Pandemic Preparing to care for patients with cancer from the perspective of low- and middle-income countries
    Galassi, Annette
    Augustinho Teixeira, Tamara Otsuru
    Lopes De Domenico, Edvane Birelo
    Al-Ruzzieh, Majeda
    Oti, Naomi Oyoe Ohene
    Sukumaran, Surya
    CLINICAL JOURNAL OF ONCOLOGY NURSING, 2020, 24 (05) : 586 - 590
  • [32] Noncommunicable Disease (NCD) strategic plans in low- and lower-middle income Sub-Saharan Africa: framing and policy response
    Boudreaux, Chantelle
    Noble, Christopher
    Coates, Matthew M.
    Kelley, Jason
    Abanda, Martin
    Kintu, Alexander
    McLaughlln, Amy
    Marx, Andrew
    Bukhman, Gene
    GLOBAL HEALTH ACTION, 2020, 13 (01)
  • [33] Setting up a Cancer Clinic in a Low-and-Middle-Income Country (LMIC) in Sub-Saharan Africa: A Case of Taita Taveta County in Kenya.
    Kitur, Gloria
    Achieng, Emmah
    Mwakichako, Rebecca
    Kimotho, Felix
    Asirwa, Chite
    CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2021, 30 (07)
  • [34] Low- and middle-income country perspective: bridging gaps in craniofacial surgery care. Challenges, innovations, and future prospects
    Waheed, Aiman
    Jha, Mayank
    Chaurasia, Bipin
    NEUROSURGICAL FOCUS, 2025, 58 (01)
  • [35] Improving the Quality of the Delivery of Nutritional Care Among Children Undergoing Treatment for Cancer in a Low- and Middle-Income Country
    Damasco-Avila, Erika
    Sagastizado, Stephany Zelaya
    Carrillo, Maria
    Blanco, Jessica
    Fu, Ligia
    Espinoza, Darrell
    Ladas, Elena J.
    JCO GLOBAL ONCOLOGY, 2023, 9 : e2300074
  • [36] Competing health priorities as barriers to cervical cancer care across low- and middle-income countries: in their own words
    Ackbarali, Tariqa
    Thomas-Purcell, Kamilah
    Edmonds, William
    Kent, Brianna
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2024, 34 (SUPPL_3) : A292 - A293
  • [37] Bonn call for action and the unfinished task of radiation protection of children and adolescents in low and middle-income countries: A focus on Sub-Saharan Africa
    Nkubli, F. B.
    Joseph, D. Z.
    Yao, B.
    Rockson, P.
    Kenyanya, J.
    Nzotta, C. C.
    RADIOGRAPHY, 2021, 27 (03) : 962 - 967
  • [38] The Effectiveness of Adequate Antenatal Care in Reducing Adverse Perinatal Outcomes: Evidence From a Low- or Middle-Income Country
    Mina, Nazmunnahar
    Nuruzzaman, Mostafa
    Habib, Mostafa Nahian
    Rahman, Mahin
    Chowdhury, Faiza Mehrab
    Ahsan, Syeda Nafisa
    Ahmed, Fabliha Fyrose
    Azizi, Shajeda
    Mubin, Nazirum
    Kibria, A. H. M. Golam
    Shuchi, Ferdous Ara
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2023, 15 (12)
  • [39] Quality intrapartum care expectations and experiences of women in sub-Saharan African Low and Low Middle-Income Countries: a qualitative meta-synthesis
    Salma A. E. Ahmed
    Abela Mahimbo
    Angela Dawson
    BMC Pregnancy and Childbirth, 23
  • [40] Quality intrapartum care expectations and experiences of women in sub-Saharan African Low and Low Middle-Income Countries: a qualitative meta-synthesis
    Ahmed, Salma A. E.
    Mahimbo, Abela
    Dawson, Angela
    BMC PREGNANCY AND CHILDBIRTH, 2023, 23 (01)