First disclosure of AZD3470, a highly potent MTA-cooperative PRMT5 inhibitor in PRIMROSE and PRIMAVERA clinical studies

被引:0
|
作者
Smith, J. [1 ]
Urosevic, J. [1 ]
Moore, S. [1 ]
Magiera, L. [1 ]
Bradshaw, L. [1 ]
Gianni, D. [2 ]
Srinivasan, B. [2 ]
Debreczeni, J. [2 ]
Stubbs, C. [2 ]
Vazquez-Chantada, M. [2 ]
Hong, T. [3 ]
Cronin, A. [1 ]
Khan, K. [1 ]
Wiseman, E. [1 ]
Ferguson, D. [3 ]
Lynch, J. [1 ]
Chan, H. M. [3 ]
Critchlow, S. [1 ]
Fawell, S. [3 ]
Dean, E. [1 ]
机构
[1] AstraZeneca, Res & Early Dev Oncol R&D, Cambridge, England
[2] AstraZeneca, Discovery Sci Biopharmaceut R&D, Cambridge, England
[3] AstraZeneca, Res & Early Dev Oncol R&D, Boston, MA USA
关键词
D O I
10.1016/j.ejca.2024.114668
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
PB134
引用
收藏
页码:S59 / S60
页数:2
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