Harnessing Electricity in Dehydrogenative Coupling: Transition Metal-Free Synthesis of Quinoline Derivatives

被引：0

作者：

Vageesh, M. ^{[1
]}

Anand, Abhijeet ^{[1
]}

Panja, Subir ^{[2
]}

Dey, Raju ^{[1
]}

机构：

[1] Natl Inst Technol Calicut, Dept Chem, Kozhikode 673601, Kerala, India

[2] Indian Inst Technol, Dept Chem, Mumbai 400076, India

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2025年

关键词：

alcohol dehydrogenation; aryl/alkyl quinolines; electrolysis; room temperature; transition metal-free; CATALYZED ALPHA-ALKYLATION; GAMMA-AMINO-ALCOHOLS; KETONES; H-2; ACCESS;

D O I：

10.1002/ejoc.202500316

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient strategy is demonstrated for the electrocatalytic synthesis of 2-aryl quinoline derivatives via an anodic dehydrogenation of 2-aminobenzyl alcohol molecules followed by condensation with carbonyl compounds at room temperature. The current protocol requires only electricity as the green oxidant, provides the desired products in good to excellent yield, and is compatible with a wide range of functional groups.

引用

页数：6

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