Management of immune-related adverse events

被引：0
|
作者：
Princk, Marika Henriette [1 ,2 ]
Pervan, Mascha [3 ]
Riedl, Joerg [1 ]
机构：
[1] Univ Klinikum Schleswig Holstein, Univ Canc Ctr Schleswig Holstein, Campus Lubeck, Lubeck, Germany
[2] Univ Klinikum Schleswig Holstein, Klin Frauenheilkunde & Geburtshilfe, Campus Lubeck,Ratzeburger Allee 160, D-23538 Lubeck, Germany
[3] Univ Klinikum Munster UKM, Klin Gynakol & Geburtshilfe, Munster, Germany
来源：
UROLOGIE | 2025年
关键词：
Immune checkpoint inhibitors; Pembrolizumab; Atezolizumab; Corticosteroids; Autoimmunity;
D O I：
10.1007/s00120-024-02517-x
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
With the implementation of immunotherapy, a completely new, broad spectrum of side effects has emerged in oncology-the immune-related adverse events (irAEs). Their management differs greatly from that of classic cytotoxic side effects and is based primarily on corticosteroids, immunomodulatory agents, and treatment interruptions. Whereas some events are low grade and reversible, others can be severe and lead to permanent disorders or even death. Therefore, early recognition and treatment in the context of interdisciplinary side effects management is critical for patients' safety, prognosis, and quality of life.
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页数：7
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