COVID-19 Vaccines Effectiveness and Safety in Trinidad and Tobago: A Systematic Review and Meta-Analysis

被引：0

作者：

Justiz-Vaillant, Angel ^{[1
]}

Roopnarine, Kimberly ^{[1
]}

Solomon, Shaundell ^{[1
]}

Phillips, Alyssa ^{[1
]}

Sandy, Solange ^{[1
]}

Subero, Alyssa ^{[1
]}

Seepersad, Sarah ^{[1
]}

Span, Nicholas ^{[1
]}

Ramnath, Phalmanie ^{[1
]}

Ramnarine, Akaasha ^{[1
]}

Ramdath, Bimala ^{[1
]}

Rampaul, Chelsea ^{[1
]}

Ramdial, Renissa ^{[1
]}

Phagoo, Dana ^{[1
]}

Ramdhanie, Thalia ^{[1
]}

Moonilal, Vinaya ^{[1
]}

Poliah, Emily-Marie ^{[1
]}

Poonwassie, Steffan ^{[1
]}

Punilal, Karishta ^{[1
]}

Panchoo, Sarah ^{[1
]}

Parris, Justice ^{[1
]}

Oudit, Steven ^{[1
]}

Muir, Trudy ^{[1
]}

Nicholas-Joseph, Johnson ^{[1
]}

Pandit, Bijey Raj ^{[1
]}

Pakeerah, Sanjeev ^{[1
]}

Sookoo, Vesham ^{[1
]}

Richards, Patrice ^{[1
]}

John, Tishia ^{[1
]}

Gopaul, Darren ^{[2
]}

Soodeen, Sachin ^{[1
]}

Arozarena-Barbosa, Odette ^{[3
]}

Williams, Arlene ^{[1
]}

Unakal, Chandrashehkar ^{[1
]}

Fundora, Rodolfo Arozarena ^{[3
,4
]}

Thompson, Reinand ^{[1
]}

Akpaka, Patrick Eberechi ^{[1
]}

机构：

[1] Univ West Indies, Dept Para Clin Sci, St Augustine Campus, St Augustine 330912, Trinidad Tobago

[2] Morehouse Sch Med, Dept Surg, Atlanta, GA 30310 USA

[3] Eric Williams Med Sci Complex, North Cent Reg Hlth Author, Champs Fleurs 330912, Trinidad Tobago

[4] Univ West Indies, Fac Med Sci, Dept Clin & Surg Sci, St Augustine 330912, Trinidad Tobago

来源：

MICROORGANISMS | 2025年 / 13卷 / 01期

关键词：

Pfizer-BioNTech; modern; Novavax; AstraZeneca; Sinopharm; Janssen; vaccine effectiveness (VE); COVID-19; Trinidad and Tobago; MYOCARDITIS; ACCEPTANCE; EFFICACY;

D O I：

10.3390/microorganisms13010135

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

This systematic review evaluated the effectiveness and side effects of various COVID-19 vaccines, with a focus on Trinidad and Tobago. The Pfizer-BioNTech and Moderna vaccines demonstrated the highest efficacy, particularly against COVID-19 variants, while Janssen and Sinopharm were comparatively less effective. mRNA vaccines, such as Pfizer-BioNTech and Oxford-AstraZeneca, were associated with more frequent and severe side effects, including soreness, fever, and cardiovascular issues. The review also identified significant gaps in the current scientific literature regarding COVID-19 vaccination issues in Trinidad and Tobago. These gaps highlight the need for comprehensive research to address vaccination challenges, including public health communication, equitable access, and local perceptions of vaccine safety. This analysis provides a foundation for developing targeted strategies to improve vaccine effectiveness in the region.

引用

页数：61

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