Andrographolide and its Derivatives in Cardiovascular Disease: A Comprehensive Review

被引：0
|
作者：
Zhang, Shenjie [1 ]
Xie, Xiaokai [1 ]
Zhao, Juan [2 ]
Jiang, Yilong [1 ]
Huang, Chao [3 ]
Li, Qi [1 ]
Xia, Boyu [1 ]
Yin, Le [2 ]
Yuan, Xiaomei [4 ]
You, Qingsheng [1 ]
机构：
[1] Nantong Univ, Dept Cardiothorac Surg, Affiliated Hosp, Nantong, Peoples R China
[2] Tongzhou Peoples Hosp, Dept Cardiol, Nantong, Peoples R China
[3] Nantong Univ, Sch Pharm, Dept Pharmacol, Nantong, Peoples R China
[4] Univ Elect Sci & Technol China, Sichuan Prov Peoples Hosp, Dept Cardiol, 32 Sect 2 West First Ring Rd, Chengdu 610072, Peoples R China
来源：
PLANTA MEDICA | 2025年
关键词：
andrographolide; cardiovascular disease; heart; CORONARY-HEART-DISEASE; NF-KAPPA-B; ATRIAL-FIBRILLATION; IN-VITRO; CARDIAC-HYPERTROPHY; OXIDATIVE STRESS; MYOCARDIAL-INFARCTION; SIGNALING PATHWAYS; PANICULATA EXTRACT; GENE-EXPRESSION;
D O I：
10.1055/a-2542-0756
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Cardiovascular disease is one of the main causes of mortality worldwide. Andrographolide represents an important category of natural phytochemicals that has significant therapeutic potential in various conditions such as acute lung injury, heart disease, and viral infections due to its anti-oxidative, anti-inflammatory, and anti-apoptotic properties. This compound plays a protective role in human pathophysiology. This review provides a comprehensive overview of the effects of andrographolide on cardiovascular disease and examines its essential roles and mechanisms in cardiovascular disease and other vascular dysfunctions. The data collected in this review serve as a comprehensive reference for the role of andrographolide in cardiovascular disease and provide valuable insights for further research and the development of andrographolide as a novel therapeutic approach for cardiovascular disease.
引用
收藏
页数：12
相关论文
共 50 条
  • [41] Comprehensive Review of Cardiovascular Complications of Coronavirus Disease 2019 and Beneficial Treatments
    Welty, Francine K.
    Rajai, Nazanin
    Amangurbanova, Maral
    CARDIOLOGY IN REVIEW, 2022, 30 (03) : 145 - 157
  • [42] Link between cardiovascular disease and the risk of falling: a comprehensive review of the evidence
    Mikos, Marcin
    Winnicki, Kamil
    Henry, Brandon M.
    Sanchis-Gomar, Fabian
    POLISH ARCHIVES OF INTERNAL MEDICINE-POLSKIE ARCHIWUM MEDYCYNY WEWNETRZNEJ, 2021, 131 (04): : 369 - 376
  • [43] The Effect of Erythropoietin and Its Derivatives on Ischemic Stroke Therapy: A Comprehensive Review
    Ma, Yuanyuan
    Zhou, Zhiyuan
    Yang, Guo-Yuan
    Ding, Jing
    Wang, Xin
    FRONTIERS IN PHARMACOLOGY, 2022, 13
  • [44] Antidepressant Potential of Quercetin and its Glycoside Derivatives: A Comprehensive Review and Update
    Chen, Shen
    Tang, Yueheng
    Gao, Yang
    Nie, Kexin
    Wang, Hongzhan
    Su, Hao
    Wang, Zhi
    Lu, Fuer
    Huang, Wenya
    Dong, Hui
    FRONTIERS IN PHARMACOLOGY, 2022, 13
  • [45] Bioactivities and Mechanisms of Action of Diphyllin and Its Derivatives: A Comprehensive Systematic Review
    Hou, Wen
    Huang, Le-Jun
    Huang, Hao
    Liu, Sheng-Lan
    Dai, Wei
    Li, Zeng-Min
    Zhang, Zhen-Yu
    Xin, Su-Ya
    Wang, Jin-Yang
    Zhang, Zi-Yun
    Ouyang, Xi
    Lan, Jin-Xia
    MOLECULES, 2023, 28 (23):
  • [46] A review of the neuroprotective effects of andrographolide in Alzheimer's disease
    Abedi, Zahra
    Basri, Hamidon
    Hassan, Zurina
    Mat, Liyana Najwa Inche
    Khaza'ai, Huzwah
    Mohamad, Nur Afiqah
    ADVANCES IN TRADITIONAL MEDICINE, 2021, 21 (02) : 253 - 266
  • [47] A review of the neuroprotective effects of andrographolide in Alzheimer's disease
    Zahra Abedi
    Hamidon Basri
    Zurina Hassan
    Liyana Najwa Inche Mat
    Huzwah Khaza’ai
    Nur Afiqah Mohamad
    Advances in Traditional Medicine, 2021, 21 : 253 - 266
  • [48] TelmisartanA Review of its Use in Cardiovascular Disease Prevention
    James E. Frampton
    Drugs, 2011, 71 : 651 - 677
  • [49] Telmisartan A Review of its Use in Cardiovascular Disease Prevention
    Frampton, James E.
    DRUGS, 2011, 71 (06) : 651 - 677
  • [50] Activity of Andrographolide and Its Derivatives against Influenza Virus in Vivo and in Vitro
    Chen, Jian-Xin
    Xue, Hui-Jun
    Ye, Wen-Cai
    Fang, Bing-Hu
    Liu, Ya-Hong
    Yuan, Shao-Hua
    Yu, Pei
    Wang, Yu-Qiang
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2009, 32 (08) : 1385 - 1391
12345