Photoinduced Carbamoylarylation of Alkynes with N-Aryl Oxamic Acids

被引：0

作者：

Sekine, Kohei ^{[1
,2
]}

Yue, Gaofan ^{[1
]}

Kajiwara, June ^{[1
]}

Wu, Di ^{[1
]}

Shiozuka, Akira ^{[1
]}

Kuninobu, Yoichiro ^{[1
,2
]}

机构：

[1] Kyushu Univ, Interdisciplinary Grad Sch Engn Sci, Dept Interdisciplinary Engn Sci, Fukuoka 8168580, Japan

[2] Kyushu Univ, Inst Mat Chem & Engn, Fukuoka 8168580, Japan

来源：

ORGANIC LETTERS | 2025年

基金：

日本学术振兴会;

关键词：

TRANSFER RADICAL-ADDITION; STEREOCONTROLLED METHOD; MIGRATION;

D O I：

10.1021/acs.orglett.5c00866

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1,2-Difunctionalization of alkynes is an attractive synthetic protocol, because it can achieve a high step economy and provide various complex organic molecules. This study demonstrates the visible-light-induced carbamoylarylation of terminal alkynes using N-aryl oxamic acids as bifunctional reagents. The transformation involves the addition of carbamoyl radicals to alkenes, resulting in 1,4-aryl migration via C(aryl)-N bond cleavage to afford the corresponding arylacrylamides in moderate to good yields.

引用

页数：5

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