Depressed TFAM promotes acetaminophen-induced hepatotoxicity regulated by DDX3X-PGC1α-NRF2 signaling pathway

被引：0
|
作者：
Chen, Sisi [1 ]
Ouyang, Qin [1 ]
Liu, Mei [2 ]
Ren, Feng [2 ]
Huang, Jian [1 ]
机构：
[1] Capital Med Univ, Beijing Friendship Hosp, Beijing, Peoples R China
[2] Capital Med Univ, Beijing Youan Hosp, Beijing, Peoples R China
来源：
JOURNAL OF HEPATOLOGY | 2024年 / 80卷
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
SAT-330
引用
收藏
页码：S121 / S122
页数：2
相关论文
共 50 条
  • [31] Tanshinone IIA attenuates acetaminophen-induced hepatotoxicity through HOTAIR-Nrf2-MRP2/4 signaling pathway
    Zhang, Xiqian
    Wang, Ting
    Yang, Yujie
    Li, Ruina
    Chen, Ya
    Li, Rong
    Jiang, Xuehua
    Wang, Ling
    BIOMEDICINE & PHARMACOTHERAPY, 2020, 130
  • [32] Shikonin Attenuates Acetaminophen-Induced Hepatotoxicity by Upregulation of Nrf2 through Akt/GSK3β Signaling (vol 24, 110, 2019)
    Li, Huachao
    Chen, Yueming
    Zhang, Jiahao
    Chen, Xiangcui
    Li, Zheng
    Liu, Bing
    Zhang, Luyong
    MOLECULES, 2023, 28 (14):
  • [33] Thrombospondin-1 Inhibition Reduces Nrf2 Activity and Increases Liver Injury during Acetaminophen-Induced Hepatotoxicity
    McMillin, Matthew
    Frampton, Gabriel
    FASEB JOURNAL, 2021, 35
  • [34] Functionalized selenium nanoparticles ameliorated acetaminophen-induced hepatotoxicity through synergistically triggering PKC6/Nrf2 signaling pathway and inhibiting CYP 2E1
    Zou, Si
    Gong, Yetao
    Li, Xiujie
    Wu, Yanbin
    Wu, Jinzhong
    Wu, Jianguo
    Wong, Ka-Hing
    FOOD SCIENCE AND HUMAN WELLNESS, 2024, 13 (02) : 932 - 945
  • [35] Puerarin protects against acetaminophen-induced oxidative damage in liver through activation of the Keap1/Nrf2 signaling pathway
    Zhou, Wanhai
    He, Heng
    Wei, Qin
    Che, Litao
    Zhao, Xin
    Liu, Wenwen
    Yan, Yue
    Hu, Lianqing
    Du, Yonghua
    Yin, Zhongqiong
    Shuai, Yongkang
    Yang, Li
    Feng, Ruizhang
    FOOD SCIENCE & NUTRITION, 2023, 11 (10): : 6604 - 6615
  • [36] Kaempferol sophoroside glucoside mitigates acetaminophen-induced hepatotoxicity: Role of Nrf2/NF-κB and JNK/ASK-1 signaling pathways
    Mohamed, Gamal A.
    El-Agamy, Dina S.
    Abdallah, Hossam M.
    Sindi, Ikhlas A.
    Almogaddam, Mohammed A.
    Alzain, Abdulrahim A.
    Andijani, Yusra Saleh
    Ibrahim, Sabrin R. M.
    HELIYON, 2024, 10 (10)
  • [37] Scopoletin alleviates acetaminophen-induced hepatotoxicity through modulation of NLRP3 inflammasome activation and Nrf2/HMGB1/TLR4/ NF-κB signaling pathway
    Yuan, Yilin
    Zhang, Jianxiu
    Li, Hui
    Yuan, Fengxia
    Cui, Qinglong
    Wu, Di
    Yuan, Haidan
    Piao, Guangchun
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2025, 148
  • [38] Disruption of Thioredoxin Reductase 1 Protects Mice from Acute Acetaminophen-Induced Hepatotoxicity through Enhanced NRF2 Activity
    Patterson, Andrew D.
    Carlson, Bradley A.
    Li, Fei
    Bonzo, Jessica A.
    Yoo, Min-Hyuk
    Krausz, Kristopher W.
    Conrad, Marcus
    Chen, Chi
    Gonzalez, Frank J.
    Hatfield, Dolph L.
    CHEMICAL RESEARCH IN TOXICOLOGY, 2013, 26 (07) : 1088 - 1096
  • [39] Dandelion polyphenols protect against acetaminophen-induced hepatotoxicity in mice via activation of the Nrf-2/HO-1 pathway and inhibition of the JNK signaling pathway
    Ren Yong-Shen
    Zheng Yao
    Duan Huan
    Lei Lei
    Deng Xin
    Liu Xin-Qiao
    Mei Zhi-Nan
    Deng Xu-Kun
    CHINESE JOURNAL OF NATURAL MEDICINES, 2020, 18 (02) : 103 - 113
  • [40] Dandelion polyphenols protect against acetaminophen-induced hepatotoxicity in mice via activation of the Nrf-2/HO-1 pathway and inhibition of the JNK signaling pathway
    REN Yong-Shen
    ZHENG Yao
    DUAN Huan
    LEI Lei
    DENG Xin
    LIU Xin-Qiao
    MEI Zhi-Nan
    DENG Xu-Kun
    Chinese Journal of Natural Medicines, 2020, 18 (02) : 103 - 113
12345