Reaching the SUMMIT? Benefits and potential risks associated with the use of tirzepatide in heart failure with preserved ejection fraction

被引:0
|
作者
Hellenkamp, Kristian [1 ,2 ]
Sato, Ryosuke [1 ,2 ]
von Haehling, Stephan [1 ,2 ]
机构
[1] Univ Gottingen, Med Ctr, Dept Cardiol & Pneumol, Robert-Koch-Str 40, D-37075 Gottingen, Germany
[2] German Ctr Cardiovasc Res DZHK, Partner Site Lower Saxony, Gottingen, Germany
来源
MED | 2025年 / 6卷 / 02期
关键词
D O I
10.1016/j.medj.2024.12.004
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The SUMMIT trial(1) showed that the dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist tirzepatide improves quality of life and reduces worsening heart failure (HF) events in patients with HF with preserved ejection fraction (HFpEF) and obesity. Some concerns, however, remain.
引用
收藏
页码:1 / 4
页数:4
相关论文
共 50 条
  • [31] Heart Failure With Preserved Ejection Fraction
    Borlaug, Barry A.
    Sharma, Kavita
    Shah, Sanjiv J.
    Ho, Jennifer E.
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2023, 81 (18) : 1810 - 1834
  • [32] Heart Failure with Preserved Ejection Fraction
    Redfield, Margaret M.
    NEW ENGLAND JOURNAL OF MEDICINE, 2016, 375 (19): : 1868 - 1877
  • [33] Heart Failure with Preserved Ejection Fraction
    Cannata, Antonio
    Mcdonagh, Theresa A.
    NEW ENGLAND JOURNAL OF MEDICINE, 2025, 392 (02): : 173 - 184
  • [34] Heart failure with preserved ejection fraction
    Rigolli, Marzia
    Whalley, Gillian A.
    JOURNAL OF GERIATRIC CARDIOLOGY, 2013, 10 (04) : 369 - 376
  • [35] Heart Failure with Preserved Ejection Fraction
    Kallikazaros, Ioannis E.
    HELLENIC JOURNAL OF CARDIOLOGY, 2014, 55 (03) : 265 - 266
  • [36] Heart failure with preserved ejection fraction
    Galinier, Michel
    PRESSE MEDICALE, 2008, 37 (7-8): : 1121 - 1131
  • [37] Heart Failure with Preserved Ejection Fraction
    Michelle Mitchell
    Current Emergency and Hospital Medicine Reports, 2019, 7 : 184 - 188
  • [38] Heart failure with preserved ejection fraction
    James D. Gladden
    Wolfgang A. Linke
    Margaret M. Redfield
    Pflügers Archiv - European Journal of Physiology, 2014, 466 : 1037 - 1053
  • [39] Heart failure with preserved ejection fraction
    Alsamara, Mershed
    Alharethi, Rami
    EXPERT REVIEW OF CARDIOVASCULAR THERAPY, 2014, 12 (06) : 743 - 750
  • [40] Heart Failure with Preserved Ejection Fraction
    Mitchell, Michelle
    CURRENT EMERGENCY AND HOSPITAL MEDICINE REPORTS, 2019, 7 (04) : 184 - 188