Advantages and challenges of polymer-lipid hybrid nanoparticles for the delivery of biotech drugs

被引：0
|
作者：
Ottonelli, Ilaria [1 ]
Baraldi, Cecilia [1 ]
Ruozi, Barbara [1 ]
Vandelli, Maria Angela [1 ]
Tosi, Giovanni [1 ]
Duskey, Jason T. [1 ]
机构：
[1] Univ Modena & Reggio Emilia, Dept Life Sci, NanotechLab, Via G Campi 103, I-41125 Modena, Italy
来源：
NANOMEDICINE | 2025年
关键词：
Polymer nanoparticles; nanoparticles; gene/drug delivery; targeting; vaccines;
D O I：
10.1080/17435889.2025.2457930
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
引用
收藏
页数：3
相关论文
共 50 条
  • [21] Polymer-Lipid Microparticles for Pulmonary Delivery
    Eleftheriadis, Georgios K.
    Akrivou, Melpomeni
    Bouropoulos, Nikolaos
    Tsibouklis, John
    Vizirianakis, Ioannis S.
    Fatouros, Dimitrios G.
    LANGMUIR, 2018, 34 (11) : 3438 - 3448
  • [22] Microfluidic hydrodynamic focusing synthesis of polymer-lipid nanoparticles for siRNA delivery
    Huang, Xueqin
    Lee, Robert J.
    Qi, Yuhang
    Li, Yujing
    Lu, Jiahui
    Meng, Qingfan
    Teng, Lesheng
    Xie, Jing
    ONCOTARGET, 2017, 8 (57) : 96826 - 96836
  • [23] Systemic delivery of mRNA and DNA to the lung using polymer-lipid nanoparticles*
    Kaczmarek, James C.
    Patel, Asha Kumari
    Rhym, Luke H.
    Palmiero, Umberto Capasso
    Bhat, Balkrishen
    Heartlein, Michael W.
    DeRosa, Frank
    Anderson, Daniel G.
    BIOMATERIALS, 2021, 275
  • [24] Cholate-modified polymer-lipid hybrid nanoparticles for oral delivery of quercetin to potentiate the antileukemic effect
    Yin, Juntao
    Hou, Yantao
    Song, Xiaoyong
    Wang, Peiqing
    Li, Yang
    INTERNATIONAL JOURNAL OF NANOMEDICINE, 2019, 14 : 4045 - 4057
  • [25] Targeted Delivery of mRNA with Polymer-Lipid Nanoparticles for In Vivo Base Editing
    Chen, Qimingxing
    Chang, Yan
    He, Xiaoyan
    Ding, Yan
    Wang, Runyuan
    Luo, Ran
    Yuan, Jialu
    Chen, Jiabei
    Zhong, Guisheng
    Yang, Huiying
    Chen, Jia
    Li, Jianfeng
    ACS NANO, 2025, 19 (08) : 7835 - 7850
  • [26] A novel polymer-lipid hybrid nanoparticle for efficient nonviral gene delivery
    Jian Li
    Ying-zi He
    Wen Li
    Yun-zhen Shen
    Yu-ru Li
    Yun-feng Wang
    Acta Pharmacologica Sinica, 2010, 31 : 509 - 514
  • [27] A novel polymer-lipid hybrid nanoparticle for efficient nonviral gene delivery
    Li, Jian
    He, Ying-zi
    Li, Wen
    Shen, Yun-zhen
    Li, Yu-ru
    Wang, Yun-feng
    ACTA PHARMACOLOGICA SINICA, 2010, 31 (04) : 509 - 514
  • [28] Stable Polymer-Lipid Hybrid Nanoparticles Based on mcl-Polyhydroxyalkanoate and Cationic Liposomes for mRNA Delivery
    Shishlyannikov, Sergey M.
    Zubkov, Ilya N.
    Vysochinskaya, Vera V.
    Gavrilova, Nina V.
    Dobrovolskaya, Olga A.
    Elpaeva, Ekaterina A.
    Maslov, Mikhail A.
    Vasin, Andrey
    PHARMACEUTICS, 2024, 16 (10)
  • [29] An update on polymer-lipid hybrid systems for improving oral drug delivery
    Maghrebi, Sajedehsadat
    Prestidge, Clive A.
    Joyce, Paul
    EXPERT OPINION ON DRUG DELIVERY, 2019, 16 (05) : 507 - 524
  • [30] Polymer-lipid hybrid nanoparticles as potential lipophilic anticancer drug carriers
    Salel, Sedef
    Iyisan, Banu
    DISCOVER NANO, 2023, 18 (01)
12345