Unhelpful CD4 help: Removal of conventional CD4+T cells promotes priming of tumor antigen-specific CD8 T cells in the context of CD4-depletion therapy

被引：0
|
作者：
Dragnev, Christo P. C.
Ramirez, Delaney E.
Searles, Tyler G.
Spicer, Nathaniel
Chen, TIffany
Lines, J. Louise
Hawkes, Aaron R.
Davis, Wilson L., III
Mohamed, Asmaa
Shirai, Keisuke
Phillips, Joesph D.
Rosato, Pamela C.
Huang, Yina H.
Turk, Mary Jo
机构：
来源：
CANCER IMMUNOLOGY RESEARCH | 2024年 / 12卷 / 10期
关键词：
D O I：
10.1158/2326-6074.TUMIMM24-A031
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
A031
引用
收藏
页数：3
相关论文
共 50 条
  • [21] Tumor Antigen-specific CD4+T cells and B cells in Human Cancers
    Ueno, Hideki
    CANCER SCIENCE, 2022, 113
  • [22] CD8 T cell priming by B lymphocytes is CD4 help dependent
    Castiglioni, P
    Gerloni, M
    Cortez-Gonzalez, X
    Zanetti, M
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2005, 35 (05) : 1360 - 1370
  • [23] In vivo activation of antigen-specific CD4 T cells
    Jenkins, MK
    Khoruts, A
    Ingulli, E
    Mueller, DL
    McSorley, SJ
    Reinhardt, RL
    Itano, A
    Pape, KA
    ANNUAL REVIEW OF IMMUNOLOGY, 2001, 19 : 23 - 45
  • [24] Direct CD4 Help Provision following Interaction of Memory CD4 and CD8 T Cells with Distinct Antigen-Presenting Dendritic Cells
    de Herve, Marie-Ghislaine de Goer
    Dembele, Bamory
    Vallee, Melissa
    Herr, Florence
    Cariou, Anne
    Taoufik, Yassine
    JOURNAL OF IMMUNOLOGY, 2010, 185 (02): : 1028 - 1036
  • [25] Genomic difference of CD4 CD8 double-positive T cells versus conventional CD4 T cells and CD8 T cells in responders undergoing immunotherapy in advanced HCC.
    Ting, Vox
    Wong, Carmen Chak-Lui
    Kwong, Yok Lam
    Yau, Thomas Chung Cheung
    CANCER RESEARCH, 2021, 81 (13)
  • [26] PERSISTENT DEPLETION OF CD4+ T-CELLS AND INVERSION OF THE CD4/CD8 T-CELL RATIO INDUCED BY ANTI-CD4 THERAPY
    HORNEFF, G
    EMMRICH, F
    REITER, C
    KALDEN, JR
    BURMESTER, GR
    JOURNAL OF RHEUMATOLOGY, 1992, 19 (12) : 1845 - 1850
  • [27] Anti-CD3 priming generates heterogeneous antigen-specific memory CD4 T cells
    Patke, DS
    Ahmadzadeh, M
    Bingaman, AW
    Farber, DL
    CLINICAL IMMUNOLOGY, 2005, 117 (02) : 125 - 132
  • [28] CD4 T cells compete with CD8 T cells for antigen during a low dose infection
    Cose, S
    Brammer, C
    Zammit, DJ
    Lefrancois, L
    IMMUNOLOGY, 2005, 116 : 80 - 80
  • [29] Trafficking of tumor antigen-specific CD4 T cells in vivo.
    Ni, HT
    Spellman, SR
    Wang, JM
    Merica, RR
    Jenkins, M
    Li, W
    Mueller, DL
    Hall, WA
    Low, WC
    CLINICAL CANCER RESEARCH, 2000, 6 : 4561S - 4561S
  • [30] Extrathymic CD4/CD8 double positive T cells
    Zuckermann, FA
    VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 1999, 72 (1-2) : 55 - 66
12345