Primary cutaneous extranodal natural killer/T-cell lymphoma (nasal-type) presenting as bilateral necrotic plaques on the feet

被引:0
|
作者
Jiang, Melinda [1 ,2 ]
Kerkemeyer, Karolina [1 ]
Newland, Kate [1 ,2 ]
机构
[1] Flinders Med Ctr, Dept Dermatol, Bedford Pk, SA 5067, Australia
[2] Univ Adelaide, Fac Hlth & Med Sci, Adelaide, SA 5005, Australia
关键词
D O I
10.1684/ejd.2024.4667
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
definite diagnosis for the lesion of the thigh was not bullae were initially resolved by the treatment, but they recurred one month later. We considered the possibility of bullous pemphigoid at that time. Histopathological examination of the skin lesion on the thigh revealed a subepidermal bulla and infiltration of lymphocytes in the dermis (figure 1F). DIF was positive for IgG and C3 in the basement membrane zone (epidermal BMZ) (figpositive IgG anti-epidermal BMZ antibodies in the dermal side of 1 mol/L NaCl-split normal human skin (figure 1G). Although CLEIA for BP180 was negative (<3 U/mL; normal range <9 U/mL), a 200-kDa protein was detected by immunoblotting using a dermal extract (figure 1H). Although the oral bullae were considered using a recombinant protein of laminin 332 to rule out the possibility of mucosal membrane pemphigoid (MMP); the result was negative. We finally made a diagnosis of co-occurrence of anti-p200 pemphigoid and bullous LP. The patient continued the topical corticosteroid treatment, and the number of bullae gradually decreased and disappeared. occurred after COVID-19 vaccination, bullae appeared 10 provide proof, it is possible that repeated COVID-19 vac
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页码:221 / 223
页数:3
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