Labelling of human breast cancer cells with PEG/biotin encapsulated B-type Y2O3: 2 O 3: Eu nanophosphors for fluorescence detection

被引:1
|
作者
Nath, Soorya G. [1 ]
Jose, Jiya [2 ]
Bhat, Sarita G. [3 ]
Anila, E. I. [1 ,4 ]
机构
[1] Union Christian Coll, Dept Phys, Optoelect & Nanomat Res Lab, Aluva 683102, Kerala, India
[2] Rajagiri Coll Social Sci, Dept Biosci, Div Microbiol, Kochi 683104, Kerala, India
[3] Cochin Univ Sci & Technol, Thrikkakara 682022, Kerala, India
[4] CHRIST Deemed Univ, Bengaluru 560029, Karnataka, India
关键词
Surface modification; PEG/biotin; Fluorescence imaging; MCF; 7; cells; YTTRIUM-OXIDE; PHOTOLUMINESCENCE; LUMINESCENCE;
D O I
10.1016/j.inoche.2024.113100
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
The development of non-toxic quantum dots (QDs) for fluorescence labelling of cancer cells can bring significant advancements in the disease detection. Such findings can effectively replace the conventional toxic fluorescent probes by virtue of its tunable optical characteristics. Through this work, we present the development of an efficient fluorescent probe based on B-type Y2O3: Eu QDs for labelling MCF 7 cell lines. The QDs surface was encapsulated by poly ethylene glycol (PEG) along with tumour targeting ligand, biotin. The luminescence capability of the QDs were established through photoluminescence experiments. The QDs were tested to be nontoxic through MTT assay. Fluorescence detection experiments on MCF 7 cells using the nanophosphor established the material's potential to serve as an efficient probe for cancer cell detection.
引用
收藏
页数:5
相关论文
共 50 条
  • [21] Hydrothermal method for Y2O3:Eu3+ uniform nanophosphors with different templates
    Jiang, Xue
    Wu, Weihong
    Li, Yuqian
    Guo, Xiaoqing
    Wang, Nan
    Song, Qingwei
    Wang, Xue
    Han, Yuanyuan
    Wang, Liyong
    MODERN PHYSICS LETTERS B, 2019, 33 (20):
  • [22] Flame synthesis of Y2O3:Eu nanophosphors using ethanol as precursor solvents
    Xiao Qin
    Yiguang Ju
    Stefan Bernhard
    Nan Yao
    Journal of Materials Research, 2005, 20 : 2960 - 2968
  • [23] Flame synthesis of Y2O3:Eu nanophosphors using ethanol as precursor solvents
    Qin, X
    Ju, YG
    Bernhard, S
    Yao, N
    JOURNAL OF MATERIALS RESEARCH, 2005, 20 (11) : 2960 - 2968
  • [24] Direct synthesis and intense luminescence of Y2O3:Eu nanophosphors by complexation combustion
    Xia, GD
    Zhou, SM
    Zhang, JJ
    Wang, SM
    Xu, J
    CHEMISTRY LETTERS, 2005, 34 (08) : 1166 - 1167
  • [25] Photoluminescence and cathodoluminescence properties of Y2O3: Eu nanophosphors prepared by combustion synthesis
    Vu, Nguyen
    Anh, Tran Kim
    Yi, Gyu-Chul
    Strek, W.
    JOURNAL OF LUMINESCENCE, 2007, 122 (776-779) : 776 - 779
  • [26] Synthesis and characterization of rod-like Y2O3 and Y2O3:Eu3+
    C. Feldmann
    J. Merikhi
    Journal of Materials Science, 2003, 38 : 1731 - 1735
  • [27] Synthesis of Er3+ Doped Y2O3 Nanophosphors
    Venkatachalam, Nallusamy
    Saito, Yu
    Soga, Kohei
    JOURNAL OF THE AMERICAN CERAMIC SOCIETY, 2009, 92 (05) : 1006 - 1010
  • [28] Microwave assisted synthesis of monodispersed Y2O3 and Y2O3:Eu3+ particles
    Khachatourian, Adrine Malek
    Golestani-Fard, Farhad
    Sarpoolaky, Hossein
    Vogt, Carmen
    Toprak, Muhammet S.
    CERAMICS INTERNATIONAL, 2015, 41 (02) : 2006 - 2014
  • [29] Synthesis and characterization of rod-like Y2O3 and Y2O3:Eu3+
    Feldmann, C
    Merikhi, J
    JOURNAL OF MATERIALS SCIENCE, 2003, 38 (08) : 1731 - 1735
  • [30] Preparation of Eu3+ doped Y2O3 and core-shell Y2O3:Eu-Y2O3 nanoparticles: Photoluminescence study
    Singh, Dorendrajit
    Singh, L. Robindro
    INDIAN JOURNAL OF ENGINEERING AND MATERIALS SCIENCES, 2009, 16 (03) : 175 - 177