Plasmonic Nanoparticles: Enhancing Early Breast Cancer Detection Through Biosensors

Developing new devices to the early detection of breast cancer via specific molecules is the key to delivering better breast cancer handling and a greater opportunity for living. Plasmonic nanoparticles (NPs) offer useful potential for early breast cancer detection due to their specific optical properties. These NPs, naturally composed of gold or silver metals, display optical properties like localized surface plasmon resonance (LSPR), where combined oscillations of electrons make intense light scattering and absorption. LSPR enables sensitive detection of biomarkers, including peptides, DNA, aptamers, and other small biomolecules. One useful application of plasmonic NPs is surface-enhanced Raman scattering (SERS), where NPs intensify the Raman signal of molecules. In this review after an introduction of breast cancer biomarkers and plasmonic NPs, a comprehensive study was presented about the application of plasmonic NPs for the primary detection of breast cancer biomarkers and their advantages in this line.