Unlocking the potential of spatial transcriptomics with custom microfluidic chips
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作者:
Bingqi Wu
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机构:
China National Center for Bioinformation
Beijing Institute of Genomics, Chinese Academy of Sciences
University of Chinese Academy ofChina National Center for Bioinformation
Bingqi Wu
[1
,2
,3
]
Yuan Gao
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机构:
China National Center for Bioinformation
Beijing Institute of Genomics, Chinese Academy of Sciences
University of Chinese Academy ofChina National Center for Bioinformation
Yuan Gao
[1
,2
,3
]
机构:
[1] China National Center for Bioinformation
[2] Beijing Institute of Genomics, Chinese Academy of Sciences
<正>Spatial transcriptomics technique detects RNA sequences(St?hl et al., 2016) and quantifies their expression in the positional context(Ke et al., 2013), which can provide important information such as cell heterogeneity, cell developmental trajectory, differential gene expression between tissue regions or sections. To date, it is becoming a powerful tool for exploring tumorigenesis(Ren et al.,2023), cerebral neurodevelopment(Shi et al., 2023), embryonic development(Arutyunyan et al., 2023),
机构:
CSIR, Natl Laser Ctr, Biophoton, ZA-0001 Pretoria, Gauteng, South Africa
Univ Cape Town, Dept Human Biol, Div Biomed Engn, ZA-7701 Cape Town, Western Cape, South AfricaCSIR, Natl Laser Ctr, Biophoton, ZA-0001 Pretoria, Gauteng, South Africa
Sekhwama, Masindi
Mpofu, Kelvin
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CSIR, Natl Laser Ctr, Biophoton, ZA-0001 Pretoria, Gauteng, South AfricaCSIR, Natl Laser Ctr, Biophoton, ZA-0001 Pretoria, Gauteng, South Africa
机构:
Hong Kong Univ Sci & Technol, Dept Chem, Kowloon, Hong Kong, Peoples R ChinaHong Kong Univ Sci & Technol, Dept Chem, Kowloon, Hong Kong, Peoples R China
Yan, Hui
Zhang, Boyang
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Hong Kong Univ Sci & Technol, Dept Chem, Kowloon, Hong Kong, Peoples R ChinaHong Kong Univ Sci & Technol, Dept Chem, Kowloon, Hong Kong, Peoples R China
Zhang, Boyang
Wu, Hongkai
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Hong Kong Univ Sci & Technol, Dept Chem, Kowloon, Hong Kong, Peoples R ChinaHong Kong Univ Sci & Technol, Dept Chem, Kowloon, Hong Kong, Peoples R China
机构:
Chinese Acad Sci, Inst Zool, Beijing, Peoples R China
Univ Chinese Acad Sci, Hangzhou Inst Adv Study, Key Lab Syst Biol, Hangzhou, Peoples R ChinaChinese Acad Sci, Inst Zool, Beijing, Peoples R China
Zhu, Junjie
Pang, Kun
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Chinese Acad Sci, Inst Zool, Beijing, Peoples R China
Univ Chinese Acad Sci, Beijing, Peoples R ChinaChinese Acad Sci, Inst Zool, Beijing, Peoples R China
Pang, Kun
Hu, Beiyu
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Chinese Acad Sci, Inst Zool, Beijing, Peoples R China
Univ Chinese Acad Sci, Hangzhou Inst Adv Study, Key Lab Syst Biol, Hangzhou, Peoples R ChinaChinese Acad Sci, Inst Zool, Beijing, Peoples R China
Hu, Beiyu
He, Ruiqiao
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Chinese Acad Sci, Inst Zool, Beijing, Peoples R China
Univ Chinese Acad Sci, Beijing, Peoples R ChinaChinese Acad Sci, Inst Zool, Beijing, Peoples R China
He, Ruiqiao
Wang, Ning
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Chinese Acad Sci, Inst Zool, Beijing, Peoples R China
Univ Chinese Acad Sci, Beijing, Peoples R ChinaChinese Acad Sci, Inst Zool, Beijing, Peoples R China
Wang, Ning
Jiang, Zewen
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Chinese Acad Sci, Inst Zool, Beijing, Peoples R China
Univ Chinese Acad Sci, Beijing, Peoples R ChinaChinese Acad Sci, Inst Zool, Beijing, Peoples R China
Jiang, Zewen
Ji, Peifeng
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Chinese Acad Sci, Inst Zool, Beijing, Peoples R ChinaChinese Acad Sci, Inst Zool, Beijing, Peoples R China
Ji, Peifeng
Zhao, Fangqing
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机构:
Chinese Acad Sci, Inst Zool, Beijing, Peoples R China
Univ Chinese Acad Sci, Hangzhou Inst Adv Study, Key Lab Syst Biol, Hangzhou, Peoples R China
Univ Chinese Acad Sci, Beijing, Peoples R ChinaChinese Acad Sci, Inst Zool, Beijing, Peoples R China