Unlocking the potential of spatial transcriptomics with custom microfluidic chips
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作者:
Bingqi Wu
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机构:
China National Center for Bioinformation
Beijing Institute of Genomics, Chinese Academy of Sciences
University of Chinese Academy ofChina National Center for Bioinformation
Bingqi Wu
[1
,2
,3
]
Yuan Gao
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机构:
China National Center for Bioinformation
Beijing Institute of Genomics, Chinese Academy of Sciences
University of Chinese Academy ofChina National Center for Bioinformation
Yuan Gao
[1
,2
,3
]
机构:
[1] China National Center for Bioinformation
[2] Beijing Institute of Genomics, Chinese Academy of Sciences
<正>Spatial transcriptomics technique detects RNA sequences(St?hl et al., 2016) and quantifies their expression in the positional context(Ke et al., 2013), which can provide important information such as cell heterogeneity, cell developmental trajectory, differential gene expression between tissue regions or sections. To date, it is becoming a powerful tool for exploring tumorigenesis(Ren et al.,2023), cerebral neurodevelopment(Shi et al., 2023), embryonic development(Arutyunyan et al., 2023),
机构:
China Natl Ctr Bioinformat, Beijing 100101, Peoples R China
Chinese Acad Sci, Beijing Inst Genom, Beijing 100101, Peoples R China
Univ Chinese Acad Sci, Beijing 100101, Peoples R ChinaChina Natl Ctr Bioinformat, Beijing 100101, Peoples R China
Wu, Bingqi
Gao, Yuan
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机构:
China Natl Ctr Bioinformat, Beijing 100101, Peoples R China
Chinese Acad Sci, Beijing Inst Genom, Beijing 100101, Peoples R China
Univ Chinese Acad Sci, Beijing 100101, Peoples R ChinaChina Natl Ctr Bioinformat, Beijing 100101, Peoples R China