Solubility study of several polyphenolic compounds in pure and binary solvents

In recent years, there has been great interest in exploring the recovery of polyphenols from natural resources. However, in studies that address this topic, results present high recovery yield but low selectivity in the extraction of these compounds. This work seeks to improve the selectivity of these processes by an appropriate selection of the solvents. To achieve this objective, the solubility of five polyphenolic compounds: trans-piceid, myricetin, quercetin, kaempferol and trans-resveratrol in pure methanol, ethyl acetate, n-propyl acetate, and butyl acetate were determined at T = 298.15 K at 0.1 MPa, as well as the solubility of quercetin and trans-piceid in three binary solvent mixtures (methanol + ethyl acetate, methanol + n-propyl acetate and methanol + butyl acetate). Experimental results for ternary systems were correlated with the combined nearly ideal binary solvent/ Redlich-Kister (CNIBS/R-K) equation.