Decarboxylative Cross-Coupling of Aryl Carboxylic Acids with Arylboronic Acids Using Ag/ZnO Catalyst under Aerobic Conditions in Aqueous Medium

Recently, transition metal-catalyzed decarboxylative cross-coupling reactions have become a novel and crucial category of organic transformations. These reactions have practical applications in constructing carbon-carbon bonds. This study presents the efficient catalytic activity of Ag/ZnO nanoparticles that were synthesized and used as a heterogeneous catalyst in the carbon-carbon bond formation starting from carboxylic acids. By utilizing the heterogeneous Ag catalyst system, the Suzuki-Miyaura coupling reaction was effectively carried out in an aqueous environment, resulting in the formation of coupling products with high yields in a relatively short period of time. The Ag/ZnO nanoparticles were thoroughly characterized using various techniques, and inductively coupled plasma. The findings affirm that the prepared catalyst, comprising Ag/ZnO nanoparticles, exhibits exceptional efficiency and selectivity, with the added advantage of being recyclable multiple times without a significant decline in catalytic activity.