Pharmaceutical Potential of Jellyfish Derived Bioactive Compounds: Classification and Their Mechanism of Action

被引:0
|
作者
Nautiyal, Shivanshu [1 ]
Singh, Simran [1 ]
Srivastava, Shivika [1 ]
Chellakkumar, Muthiah [1 ]
Balde, Akshad [1 ]
Benjakul, Soottawat [2 ,3 ]
Nazeer, Rasool Abdul [1 ]
机构
[1] Sri Ramaswamy Mem Inst Sci & Technol, Sch Bioengn, Dept Biotechnol, Biopharmaceut Lab, Kattankulathur 603203, Tamilnadu, India
[2] Prince Songkla Univ, Fac Agroind, Int Ctr Excellence Seafood Sci & Innovat, Hat Yai 90110, Songkhla, Thailand
[3] Kyung Hee Univ, Dept Food & Nutr, Seoul 02447, South Korea
关键词
Anti-inflammation; Anti-cancer; Anti-oxidant; Bioactive compound; BOX JELLYFISH; ANTICOAGULANT ACTIVITY; CHIRONEX-FLECKERI; VENOM PROTEINS; AURELIA-AURITA; COLLAGEN; ANTIOXIDANT; PEPTIDES; TENTACLE; CNIDARIA;
D O I
10.1007/s43450-025-00631-1
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Jellyfish, a fascinating and varied group of gelatinous marine organisms, have garnered recent attention in the scientific community for their potential as rich sources of bioactive compounds with significant therapeutic implications. Characterized by bell-shaped bodies and trailing tentacles equipped with stinging cells known as "cnidocytes," jellyfish navigate the oceans with unique mechanisms for delivering toxins through organelles called nematocysts. Within the Cnidaria phylum, jellyfish span various subclasses, including cubozoans, scyphozoans, hydrozoans, and staurozoans. These captivating organisms boast a myriad of bioactive compounds, demonstrating considerable therapeutic potential. Among their notable effects are anti-inflammatory properties, anti-cancer potentials, immunomodulatory capabilities, and anti-oxidant activities. These bioactive compounds operate through diverse mechanisms, showcasing versatility in their therapeutic applications. Few compounds hint at potential treatments for inflammatory conditions, while others may interfere with cancer cell growth. Additionally, these compounds exhibit properties associated with anti-aging and antioxidation effects. Furthermore, they display promise in immunomodulation by influencing immune system activities. This review delves into the exploration of various bioactive compounds derived from different species of jellyfish, shedding light on their diverse therapeutic applications. The unique characteristics and mechanisms of action of these compounds are also discussed, presenting exciting avenues for further research and development in medicine and biotechnology.
引用
收藏
页码:291 / 307
页数:17
相关论文
共 50 条
  • [31] Biotransformation of Bioactive Natural Products for Pharmaceutical Lead Compounds
    Liu, Ji-Hua
    Yu, Bo-Yang
    CURRENT ORGANIC CHEMISTRY, 2010, 14 (14) : 1400 - 1406
  • [32] Bioactive compounds derived from echinoderms
    Gomes, Ana R.
    Freitas, Ana C.
    Rocha-Santos, Teresa A. P.
    Duarte, Armando C.
    RSC ADVANCES, 2014, 4 (56) : 29365 - 29382
  • [33] Application progress of bioactive compounds in microalgae on pharmaceutical and cosmetics
    Zhuang, Dingling
    He, Ning
    Khoo, Kuan Shiong
    Ng, Eng-Poh
    Chew, Kit Wayne
    Ling, Tau Chuan
    CHEMOSPHERE, 2022, 291
  • [34] An ethnobotanical survey of medicinal plants of Laos toward the discovery of bioactive compounds as potential candidates for pharmaceutical development
    Soejarto, D. D.
    Gyllenhaal, C.
    Kadushin, M. R.
    Southavong, B.
    Sydara, K.
    Bouamanivong, S.
    Xaiveu, M.
    Zhang, H. -J.
    Franzblau, S. G.
    Tan, Ghee T.
    Pezzuto, J. M.
    Riley, M. C.
    Elkington, B. G.
    Waller, D. P.
    PHARMACEUTICAL BIOLOGY, 2012, 50 (01) : 42 - 60
  • [35] Algae-derived bioactive compounds as potential pharmaceuticals for cancer therapy: A comprehensive review
    Minhas, Lubna Anjum
    Kaleem, Muhammad
    Farooqi, Hafiz Muhammad Umer
    Kausar, Farzana
    Waqar, Rooma
    Bhatti, Theophilus
    Aziz, Shahid
    Jung, Dong Won
    Mumtaz, Abdul Samad
    ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS, 2024, 78
  • [36] Potential Pharmacological Resources: Natural Bioactive Compounds from Marine-Derived Fungi
    Jin, Liming
    Quan, Chunshan
    Hou, Xiyan
    Fan, Shengdi
    MARINE DRUGS, 2016, 14 (04)
  • [37] The Anti-Hypertensive and Hypoglycemic Potential of Bioactive Compounds Derived from Pulasan Rind
    Tan, Seok Shin
    Tan, Seok Tyug
    Tan, Chin Xuan
    PROCESSES, 2022, 10 (03)
  • [38] Biochemical properties of bioactive peptides derived from milk proteins: Potential nutraceuticals for food and pharmaceutical applications
    Meisel, H
    LIVESTOCK PRODUCTION SCIENCE, 1997, 50 (1-2): : 125 - 138
  • [39] Sea buckthorn, its bioactive constituents, and mechanism of action: potential application in female reproduction
    Mihal, Michal
    Roychoudhury, Shubhadeep
    Sirotkin, Alexander V.
    Kolesarova, Adriana
    FRONTIERS IN ENDOCRINOLOGY, 2023, 14
  • [40] NUTRACEUTICAL POTENTIAL OF BIOACTIVE BERRY COMPOUNDS
    Velciov, Ariana-Bianca
    Rivis, Adrian
    Popescu, Sofia
    Cozma, Antoanela
    Gabriel, Bujanca
    NANO, BIO AND GREEN - TECHNOLOGIES FOR A SUSTAINABLE FUTURE CONFERENCE PROCEEDINGS, SGEM 2016, VOL I, 2016, : 669 - 676