BATokines in metabolic liver disease: good cops or bad cops?

被引：0

作者：

Pereira, Renata O. ^{[1
]}

Abel, E. Dale ^{[2
]}

机构：

[1] Univ Iowa, Roy J & Lucille A Carver Coll Med, Eagles Diabet Res Ctr, Div Endocrinol Metab & Diabet & Fraternal Order, Iowa City, IA USA

[2] Univ Calif Los Angeles, David Geffen Sch Med, Dept Med, Los Angeles, CA 90095 USA

来源：

EMBO JOURNAL | 2024年

关键词：

D O I：

10.1038/s44318-024-00239-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The systemic regulation of metabolic dysfunction-associated liver disease remains poorly understood. In this issue, Hsiao et al (2024) identify PCPE-1 as a brown-adipose tissue-derived mediator of hepatic fibrosis, integrating context-dependent ER stress-signaling. Recent work identifies PCPE-1 as a brown-adipose tissue-derived systemic mediator of liver fibrosis in metabolic dysfunction-associated steatohepatitis.

引用

页码：4807 / 4809

页数：3

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