BATokines in metabolic liver disease: good cops or bad cops?

被引：0
|
作者：
Pereira, Renata O. [1 ]
Abel, E. Dale [2 ]
机构：
[1] Univ Iowa, Roy J & Lucille A Carver Coll Med, Eagles Diabet Res Ctr, Div Endocrinol Metab & Diabet & Fraternal Order, Iowa City, IA USA
[2] Univ Calif Los Angeles, David Geffen Sch Med, Dept Med, Los Angeles, CA 90095 USA
来源：
EMBO JOURNAL | 2024年
关键词：
D O I：
10.1038/s44318-024-00239-6
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The systemic regulation of metabolic dysfunction-associated liver disease remains poorly understood. In this issue, Hsiao et al (2024) identify PCPE-1 as a brown-adipose tissue-derived mediator of hepatic fibrosis, integrating context-dependent ER stress-signaling. Recent work identifies PCPE-1 as a brown-adipose tissue-derived systemic mediator of liver fibrosis in metabolic dysfunction-associated steatohepatitis.
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页码：4807 / 4809
页数：3
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