Perioperative nivolumab results in favourable long-term outcomes in patients with locally advanced resectable non-small-cell lung cancer

被引:0
|
作者
Cascone, Tina [1 ]
William Jr, William N. [2 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Dept Thorac Head & Neck Med Oncol, Houston, TX 77030 USA
[2] Grp Oncoclin, Sao Paulo, Brazil
关键词
D O I
10.1038/s41571-024-00976-x
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
As one of the first studies testing perioperative anti-PD-(L)1 antibodies in resectable non-small- cell lung cancer (NSCLC), NADIM now confirms, in its final report, impressive 5-year clinical outcomes and that a pCR following neoadjuvant therapy translates into improved long-term survival. These data support the development of novel, personalized treatments for locally advanced resectable NSCLC.
引用
收藏
页码:81 / 82
页数:2
相关论文
共 50 条
  • [21] Duration of nivolumab for pretreated, advanced non-small-cell lung cancer
    Geier, Margaux
    Descourt, Renaud
    Corre, Romain
    Leveiller, Guillaume
    Lamy, Regine
    Goarant, Eric
    Bizec, Jean-Louis
    Bernier, Cyril
    Quere, Gilles
    Amrane, Karim
    Gaye, Elisabeth
    Lucia, Francois
    Burte, Emilie
    Chouaid, Christos
    Robinet, Gilles
    CANCER MEDICINE, 2020, 9 (19): : 6923 - 6932
  • [22] The Long-Term Outcomes of Induction Chemoradiotherapy Followed by Surgery for Locally Advanced Non-Small Cell Lung Cancer
    Uramoto, Hidetaka
    Akiyama, Hirohiko
    Nakajima, Yuki
    Kinoshita, Hiroyasu
    Inoue, Takuya
    Kurimoto, Futoshi
    Nishimura, Yu
    Saito, Yoshihiro
    Sakai, Hiroshi
    Kobayashi, Kunihiko
    CASE REPORTS IN ONCOLOGY, 2014, 7 (03): : 700 - 710
  • [23] Blood cell count indexes as predictors of outcomes in advanced non-small-cell lung cancer patients treated with Nivolumab
    Carlo Putzu
    Diego Luigi Cortinovis
    Francesca Colonese
    Stefania Canova
    Ciriaco Carru
    Angelo Zinellu
    Panagiotis Paliogiannis
    Cancer Immunology, Immunotherapy, 2018, 67 : 1349 - 1353
  • [24] Nivolumab plus Ipilimumab in Advanced Non-Small-Cell Lung Cancer
    Hellmann, M. D.
    Paz-Ares, L.
    Bernabe Caro, R.
    Zurawski, B.
    Kim, S. -W.
    Carcereny Costa, E.
    Park, K.
    Alexandru, A.
    Lupinacci, L.
    de la Mora Jimenez, E.
    Sakai, H.
    Albert, I.
    Vergnenegre, A.
    Peters, S.
    Syrigos, K.
    Barlesi, F.
    Reck, M.
    Borghaei, H.
    Brahmer, J. R.
    O'Byrne, K. J.
    Geese, W. J.
    Bhagavatheeswaran, P.
    Rabindran, S. K.
    Kasinathan, R. S.
    Nathan, F. E.
    Ramalingam, S. S.
    NEW ENGLAND JOURNAL OF MEDICINE, 2019, 381 (21): : 2020 - 2031
  • [25] Early and long-term results of lung resection for non-small-cell lung cancer in patients with severe ventilatory impairment
    Magdeleinat, P
    Seguin, A
    Alifano, M
    Boubia, S
    Regnard, JF
    EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 2005, 27 (06) : 1099 - 1105
  • [26] Which non-small-cell lung cancer patients achieve long-term survival?
    Ahbeddou, N.
    Fetohi, M.
    Boutayeb, S.
    Errihani, H.
    INDIAN JOURNAL OF CANCER, 2011, 48 (04) : 514 - U1
  • [27] Pulmonary Resection for Non-small-cell Lung Cancer in Patients on Hemodialysis: Clinical Outcome and Long-term Results
    Paola Ciriaco
    Monica Casiraghi
    Giulio Melloni
    Angelo Carretta
    Lidia Libretti
    Giuseppe Augello
    Piero Zannini
    World Journal of Surgery, 2005, 29 : 1516 - 1519
  • [28] Pulmonary resection for non-small-cell lung cancer in patients on hemodialysis: Clinical outcome and long-term results
    Ciriaco, P
    Casiraghi, M
    Melloni, G
    Carretta, A
    Libretti, L
    Augello, G
    Zannini, P
    WORLD JOURNAL OF SURGERY, 2005, 29 (11) : 1516 - 1519
  • [29] Long-term survival in patients with advanced melanoma, renal cell carcinoma, or non-small cell lung cancer treated with nivolumab
    Topalian, Suzanne L.
    Hodi, F. Stephen
    Brahmer, Julie R.
    Gettinger, Scott N.
    Smith, David C.
    McDermott, David F.
    Powderly, John D.
    Sosman, Jeffrey A.
    Atkins, Michael B.
    Spigel, David R.
    Antonia, Scott J.
    Drilon, Alexander
    Bhore, Rafia
    Hosein, Fareeda
    Sznol, Mario
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2017, 5
  • [30] Retrospective analysis of long-term survival factors in patients with advanced non-small cell lung cancer treated with nivolumab
    Murakami, Yusuke
    Tamiya, Akihiro
    Taniguchi, Yoshihiko
    Adachi, Yuichi
    Enomoto, Takatoshi
    Azuma, Koji
    Inagaki, Yuji
    Kouno, Shunichi
    Matsuda, Yoshinobu
    Okishio, Kyoichi
    Atagi, Shinji
    THORACIC CANCER, 2022, 13 (04) : 593 - 601