Ni-catalyzed reductive cyanation of alkenyl tosylates and triflates

被引：0

作者：

Graham, Joshua M. ^{[1
]}

Rousseaux, Sophie A. L. ^{[1
]}

机构：

[1] Univ Toronto, Dept Chem, Davenport Res Labs, 80 St George St, Toronto, ON M5S 3H6, Canada

来源：

CHEMICAL COMMUNICATIONS | 2025年 / 61卷 / 05期

基金：

加拿大自然科学与工程研究理事会; 加拿大创新基金会;

关键词：

REAGENTS; BOND;

D O I：

10.1039/d4cc04972a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Herein, we disclose the nickel-catalyzed reductive cyanation of alkenyl tosylates and triflates. Both cyclic and acyclic alkenyl nitriles are produced in moderate to good yield using 2-(4-methoxyphenyl)-2-methylmalononitrile (MeO-MPMN), a novel transnitrilation, or nitrile transfer, reagent. A robustness screen was undertaken to demonstrate the functional group tolerance of this method.

引用

页码：893 / 896

页数：4

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