Well-defined cobalt(<sc>ii</sc>)-catalyzed synthesis of perimidine derivatives via acceptorless dehydrogenative annulation

被引：1

作者：

Pal, Debjyoti ^{[1
]}

Sarmah, Rajashri ^{[1
]}

Mondal, Avijit ^{[1
]}

Mallick, Itu ^{[1
]}

Srimani, Dipankar ^{[1
]}

机构：

[1] Indian Inst Technol Guwahati, Dept Chem, Gauhati 781039, Assam, India

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2024年 / 22卷 / 43期

关键词：

CONVERSION; COMPLEXES; BIOMASS;

D O I：

10.1039/d4ob01306a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The versatility of the perimidine moiety offers a rich playground for researchers in fields ranging from medical science to industrial chemistry. Herein, we describe the first Co-catalyzed synthesis of 2,3-dihydro-1H-perimidine via acceptorless dehydrogenative annulation (ADA). Apart from featuring benzyl alcohol having different functionalities, heteroaryl and aliphatic alcohols also provide good yields. Our catalytic protocol is also suitable for different fatty alcohols for furnishing perimidine derivatives, keeping distal unsaturation intact. Several kinetic and control tests were carried out in order to understand the reaction sequence.

引用

页码：8602 / 8607

页数：6

共 44 条

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