Transcriptional control of interferon-stimulated genes

被引：1
|
作者：
Babadei, Olga [1 ,2 ]
Strobl, Birgit [3 ]
Decker, Thomas [2 ]
机构：
[1] Vienna Bioctr Campus VBC, Max Perutz Labs, Vienna, Austria
[2] Univ Vienna, Ctr Mol Biol, Dept Microbiol Immunobiol & Genet, Vienna, Austria
[3] Univ Vet Med Vienna, Inst Anim Breeding & Genet, Vienna, Austria
来源：
JOURNAL OF BIOLOGICAL CHEMISTRY | 2024年 / 300卷 / 10期
基金：
奥地利科学基金会;
关键词：
SEQUENCE-BINDING-PROTEIN; REGULATORY FACTOR FAMILY; IFN-GAMMA; NEGATIVE REGULATION; ANTIVIRAL IMMUNITY; TARGET GENES; STAT1; EXPRESSION; INDUCTION; KINASE;
D O I：
10.1016/j.jbc.2024.107771
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Interferon-induced genes are among the best-studied groups of coregulated genes. Nevertheless, intense research into their regulation, supported by new technologies, is continuing to provide insights into their many layers of transcriptional regulation and to reveal how cellular transcriptomes change with pathogen-induced innate and adaptive immunity. This article gives an overview of recent fi ndings on interferon- induced gene regulation, paying attention to contributions beyond the canonical JAK-STAT pathways.
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收藏
页数：14
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