Point-of-care detection of diquat and paraquat poisoning by surface-enhanced Raman spectroscopy

被引：0

作者：

Li, Wanru ^{[1
]}

Hu, Peishan ^{[1
]}

Zou, Wei ^{[1
]}

Song, Liqun ^{[1
]}

Chen, Xuelei ^{[1
]}

Shang, Ming ^{[2
]}

Wang, Cuijuan ^{[1
]}

机构：

[1] Physical and Chemical Laboratory, Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan,250000, China

[2] Shandong Cancer Hospital and Institute, Shandong Provincial Key Laboratory of Precision Oncology, Jinan,250000, China

来源：

Chinese Journal of Analysis Laboratory | 2024年 / 43卷 / 12期

关键词：

Body fluids - Nuclear radiation spectroscopy - Portable equipment - Surface scattering;

D O I：

10.13595/j.cnki.issn1000-0720.2023092301

中图分类号：

学科分类号：

摘要：

Herein, a portable kit was developed based on surface-enhanced Raman spectroscopy( SERS) technology. The kit was designed to incorporate a gold/silver core-shell nanocolloid solution, which served as the SERS active substrate. Employing this innovative approach, the point-of-care detection of diquat and paraquat in urine was successfully achieved. For diquat analysis, the linear range was from 1 μg/L to 1 mg/L (r2=0.981), with a detection limit of 0.38 μg/L and recoveries ranging from 81.9% to 87.2%. In the case of paraquat, the linear range extended from 5 μg/L to 500 μg/L (r2=0.956), with a detection limit of 1.56 μg/L and recoveries ranging from 88.6% to 114.2%. Notably, this portable kit possesses an affordable cost, facile operation, and suitability for rapid on-site detection. © 2024, Youke Publishing Co.,Ltd. All rights reserved.

引用

页码：1672 / 1678

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