Computational simulations are widely adopted in cardiovascular biomechanics because of their capability of producing physiological data otherwise impossible to measure with non-invasive modalities. Objective. This study presents openBF, a computational library for simulating the blood dynamics in the cardiovascular system. Approach. openBF adopts a one-dimensional viscoelastic representation of the arterial system, and is coupled with zero-dimensional windkessel models at the outlets. Equations are solved by means of the finite-volume method and the code is written in Julia. We assess its predictions by performing a multiscale validation study on several domains available from the literature. Main results. At all scales, which range from individual arteries to a population of virtual subjects, openBF's solution show excellent agreement with the solutions from existing software. For reported simulations, openBF requires low computational times. Significance. openBF is easy to install, use, and deploy on multiple platforms and architectures, and gives accurate prediction of blood dynamics in short time-frames. It is actively maintained and available open-source on GitHub, which favours contributions from the biomechanical community.
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Univ Rochester, Lab Laser Energet, Rochester, NY 14623 USA
Univ Rochester, Flash Ctr Computat Sci, Dept Phys & Astron, Rochester, NY 14627 USA
Univ Rochester, Dept Mech Engn, Rochester, NY 14623 USACranfield Univ, Ctr Computat Engn Sci, Cranfield MK43 0AL, England
Farmakis, Pericles S.
Fu, Lin
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Hong Kong Univ Sci & Technol, Dept Mech & Aerosp Engn, Kowloon, Clear Water Bay, Hong Kong, Peoples R China
Hong Kong Univ Sci & Technol, Dept Math, Kowloon, Clear Water Bay, Hong Kong, Peoples R ChinaCranfield Univ, Ctr Computat Engn Sci, Cranfield MK43 0AL, England
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US Air Force Acad, High Performance Comp Res Ctr, Colorado Springs, CO 80840 USAUS Air Force Acad, High Performance Comp Res Ctr, Colorado Springs, CO 80840 USA
Ghoreyshi, Mehdi
Jirasek, Adam
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US Air Force Acad, High Performance Comp Res Ctr, Colorado Springs, CO 80840 USAUS Air Force Acad, High Performance Comp Res Ctr, Colorado Springs, CO 80840 USA
Jirasek, Adam
Miller, Tyler
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Univ Colorado, Dept Mech & Aerosp Engn, Colorado Springs, CO 80918 USAUS Air Force Acad, High Performance Comp Res Ctr, Colorado Springs, CO 80840 USA
Miller, Tyler
Nuzum, Michael
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Univ Colorado, Dept Mech & Aerosp Engn, Colorado Springs, CO 80918 USAUS Air Force Acad, High Performance Comp Res Ctr, Colorado Springs, CO 80840 USA
Nuzum, Michael
Greenwood, Roger
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US Air Force Acad, High Performance Comp Res Ctr, Colorado Springs, CO 80840 USAUS Air Force Acad, High Performance Comp Res Ctr, Colorado Springs, CO 80840 USA
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Nguyen Tat Thanh Univ, Fac Med, Dept Med Phys, 298-300A Nguyen Tat Thanh St,Ward 13,Dist 4, Ho Chi Minh City, VietnamNguyen Tat Thanh Univ, Fac Med, Dept Med Phys, 298-300A Nguyen Tat Thanh St,Ward 13,Dist 4, Ho Chi Minh City, Vietnam
Tai, Duong Thanh
Omer, Hiba
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Imam Abdulrahman Bin Faisal Univ, Dept Basic Sci, Deanship Preparatory Year & Supporting Studies, POB 1982, Dammam 34212, Saudi ArabiaNguyen Tat Thanh Univ, Fac Med, Dept Med Phys, 298-300A Nguyen Tat Thanh St,Ward 13,Dist 4, Ho Chi Minh City, Vietnam
Omer, Hiba
Quoc, Le Cuong
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Ho Chi Minh City Oncol Hosp, Dept Radiat Technol, Ho Chi Minh City, VietnamNguyen Tat Thanh Univ, Fac Med, Dept Med Phys, 298-300A Nguyen Tat Thanh St,Ward 13,Dist 4, Ho Chi Minh City, Vietnam
Quoc, Le Cuong
Hai, Nguyen Xuan
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Vietnam Atom Energy Inst, Dalat Nucl Res Inst, Da Lat, VietnamNguyen Tat Thanh Univ, Fac Med, Dept Med Phys, 298-300A Nguyen Tat Thanh St,Ward 13,Dist 4, Ho Chi Minh City, Vietnam
Hai, Nguyen Xuan
Minh, Truong Van
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Dong Nai Univ, Dept Nat Sci, Dong Nai, VietnamNguyen Tat Thanh Univ, Fac Med, Dept Med Phys, 298-300A Nguyen Tat Thanh St,Ward 13,Dist 4, Ho Chi Minh City, Vietnam
Minh, Truong Van
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Sulieman, Abdelmoneim
Mattar, Essam
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King Saud Univ, Coll Appl Med Sci, Radiol Sci Dept, Riyadh, Saudi ArabiaNguyen Tat Thanh Univ, Fac Med, Dept Med Phys, 298-300A Nguyen Tat Thanh St,Ward 13,Dist 4, Ho Chi Minh City, Vietnam
Mattar, Essam
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Toufig, Hind
Tamam, N.
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Princess Nourah Bint Abdulrahman Univ, Coll Sci, Dept Phys, POB 84426, Riyadh 11671, Saudi ArabiaNguyen Tat Thanh Univ, Fac Med, Dept Med Phys, 298-300A Nguyen Tat Thanh St,Ward 13,Dist 4, Ho Chi Minh City, Vietnam
Tamam, N.
Bradley, David A.
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Univ Surrey, Ctr Nucl & Radiat Phys, Sch Math & Phys, Dept Phys, Guildford GU2 7XH, England
Sunway Univ, Ctr Appl Phys & Radiat Technol, Sunway, MalaysiaNguyen Tat Thanh Univ, Fac Med, Dept Med Phys, 298-300A Nguyen Tat Thanh St,Ward 13,Dist 4, Ho Chi Minh City, Vietnam
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Max Planck Inst Biol Cybernet, High Field Magnet Resonance, Tubingen, Germany
Univ Tubingen, Fac Sci, Tubingen, GermanyMax Planck Inst Biol Cybernet, High Field Magnet Resonance, Tubingen, Germany
Borbath, Tamas
Murali-Manohar, Saipavitra
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Max Planck Inst Biol Cybernet, High Field Magnet Resonance, Tubingen, Germany
Univ Tubingen, Fac Sci, Tubingen, GermanyMax Planck Inst Biol Cybernet, High Field Magnet Resonance, Tubingen, Germany
Murali-Manohar, Saipavitra
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Dorst, Johanna
Wright, Andrew Martin
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Max Planck Inst Biol Cybernet, High Field Magnet Resonance, Tubingen, Germany
IMPRS Cognit & Syst Neurosci, Tubingen, GermanyMax Planck Inst Biol Cybernet, High Field Magnet Resonance, Tubingen, Germany
Wright, Andrew Martin
Henning, Anke
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Max Planck Inst Biol Cybernet, High Field Magnet Resonance, Tubingen, Germany
UT Southwestern Med Ctr, Adv Imaging Res Ctr, Dallas, TX USAMax Planck Inst Biol Cybernet, High Field Magnet Resonance, Tubingen, Germany