Synthesis of tritiated N-[4-(2,4-diaminopteridine-6-methyl)-3,4-dihydro-2H-1,4- benzothiazine-7-carbonyl]-L-homo glutamic acid (MX-68)

被引：0
|
作者：
Matsuoka, Hiroharu [1 ]
Kuroki, Toshio [1 ]
Yano, Keiichi [1 ]
Takeda, Yasuhisa [1 ]
机构：
[1] Fuji Gotemba Research Laboratories, Chugai Pharmaceutical Co., Ltd., 1-135 Komakado, Gotemba, Shizuoka 412, Japan
来源：
Journal of Labelled Compounds and Radiopharmaceuticals | 1997年 / 39卷 / 05期
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：363 / 368
相关论文
共 50 条
  • [31] EARLY CLINICAL-STUDIES WITH CB3717 ((N-(4-(N-(2-AMINO-4-HYDROXY-6-QUINAZOLINYL)METHYL)PROP-2-YNYLAMINO)BENZOYL)-L-GLUTAMIC ACID
    CALVERT, AH
    ALISON, DL
    WILTSHAW, E
    BAKER, JW
    ROBINSON, B
    MOONEY, C
    MCELWAIN, TJ
    HARRAP, KR
    PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, 1984, 25 (MAR): : 165 - 165
  • [32] SYNTHESIS OF N-[P-[[(2-AMINO-3,4-DIHYDRO-4-OXO-6-PTERIDINYL)-MEHYL]AMINO]THENOYL]-L-GLUTAMIC ACID
    GURINA, SL
    PUSHKAREVA, ZV
    VOLKOVA, NV
    ANDREEVA, NA
    ZUBOVA, TE
    BIOORGANICHESKAYA KHIMIYA, 1977, 3 (08): : 1133 - 1134
  • [33] Synthesis of N-{4-[2-(2-amino-3,4-dihydro-4-oxo-7H-pyrrolo[2,3-(d)under-bar]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acid (LY231514) and analogues
    Taylor, EC
    Kuhnt, D
    Shih, CA
    CHEMISTRY AND BIOLOGY OF PTERIDINES AND FOLATES 1997, 1997, : 83 - 91
  • [34] 3-chloro-N-[7-fluoro-3-oxo-4-(prop-2-ynyl)-3,4-dihydro-2H-1,4-benzoxazin-6-yl]-2,2-dimethylpropionamide
    Cao, DY
    Chen, LG
    Song, J
    Feng, RX
    Lou, KX
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2004, 60 : O1788 - O1789
  • [35] THE DESIGN AND SYNTHESIS OF A NOVEL FOLATE ANTI-METABOLITE N-(4-(N-((2-AMINO-4-HYDROXY-6-QUINAZOLINYL) METHYL) PROP-2 YNYLAMINO)BENZYL)-L-GLUTAMIC ACID (CB-3717)
    JONES, TR
    CALVERT, AH
    JACKMAN, AL
    HARRAP, KR
    BRITISH JOURNAL OF CANCER, 1980, 42 (01) : 172 - 172
  • [36] 1,4-Dihydro-6-methyl-5-(N-methylcarbamoyl)-4-(4-nitrophenyl)pyrimidine-2(3H)-thione monohydrate
    Sridhar, B
    Ravikumar, K
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2005, 61 : O4130 - O4132
  • [37] ELECTROCHEMICAL OXIDATION OF AROMATIC ETHERS .7. OXIDATION OF 4-(3,4-DIMETHOXYBENZYL)-6,7-DIMETHOXY-2-METHYL-1,4-DIHYDRO-3(2H)-ISOQUINOLONE AND RELATED-COMPOUNDS
    BIRD, P
    POWELL, M
    SAINSBURY, M
    SCOPES, DIC
    JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1983, (09): : 2053 - 2058
  • [38] 4-[2-(Anthracen-9-ylmethylidene)-hydrazinylidene]-3-chloro-1-methyl-3,4-dihydro-1H-2 lambda(6),1-benzothiazine-2,2-dione
    Shafiq, Muhammad
    Tahir, M. Nawaz
    Khan, Islam Ullah
    Bokhari, Tanveer Hussain
    Asghar, Muhammad Nadeem
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O1788 - +
  • [39] Synthesis and biological activity of N-alkyl-6-(3-chloro-4-chloromethyl-2-oxopyrrolidin-1-yl)-7-fluoro-3,4-dihydro-2H-1,4-benzoxazin-3-one derivatives
    Pang, Huai-Lin
    Yang, Hai
    Yin, Du-Lin
    Lei, Man-Xiang
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2007, 27 (09) : 1130 - 1136
  • [40] Design and synthesis of N-[4-(2,4-diamino-5-propyl-7H-pyrrolo [2,3-D] pyrimidin-6-ylsulfanyl)-benzoyl]-L-glutamic acid as a potent inhibitor of dihydrofolate reductase and as an antitumor agent.
    Gangjee, A
    Jain, H
    Queener, SF
    Kisliuk, RL
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 229 : U197 - U197
12345