Antisense oligonucleotides targeted against human immunodeficiency virus

被引:0
|
作者
Friesen, Albert D. [1 ]
机构
[1] Genesys Pharma Inc, Winnipeg, Canada
来源
Biotechnology Advances | 1997年 / 15卷 / 3-4期
关键词
Genetic engineering - Immunology - Oligomers - Viruses;
D O I
暂无
中图分类号
学科分类号
摘要
The present invention is directed to oligonucleotides comprising nucleotide sequences sufficiently complementary to conserved regions of human immunodeficiency virus genetic material such that when bound to said region, the oligonucleotides effectively prevent expression of the genetic material.
引用
收藏
页码:782 / 783
相关论文
共 50 条
  • [31] Salvage treatment against human immunodeficiency virus
    Battegay, M
    Harr, T
    Sponagel, L
    ANNALS OF MEDICINE, 1999, 31 (04) : 253 - 260
  • [32] An approach to vaccines against human immunodeficiency virus
    Girard, M
    BarreSinoussi, F
    vanderRyst, E
    Fultz, P
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 1996, 12 (05) : 461 - 463
  • [34] Identification and preclinical pharmacology of antisense oligonucleotides targeted to human SOD1 for the treatment of ALS
    Swayze, Eric
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253
  • [35] ANTISENSE PHOSPHOROTHIOATE OLIGODEOXYNUCLEOTIDES TARGETED TO THE VPR GENE INHIBIT HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REPLICATION IN PRIMARY HUMAN MACROPHAGES
    BALOTTA, C
    LUSSO, P
    CROWLEY, R
    GALLO, RC
    FRANCHINI, G
    JOURNAL OF VIROLOGY, 1993, 67 (07) : 4409 - 4414
  • [36] Targeted delivery of antisense oligonucleotides to parenchymal liver cells in vivo
    Biessen, EAL
    Vietsch, H
    Rump, ET
    Fluiter, K
    Bijsterbosch, MK
    van Berkel, TJC
    ANTISENSE TECHNOLOGY, PT B, 2000, 314 : 324 - 342
  • [37] IN-VITRO SELECTION OF ANTISENSE OLIGONUCLEOTIDES TARGETED TO A HAIRPIN STRUCTURE
    MISHRA, RK
    TOULME, JJ
    COMPTES RENDUS DE L ACADEMIE DES SCIENCES SERIE III-SCIENCES DE LA VIE-LIFE SCIENCES, 1994, 317 (11): : 977 - 982
  • [38] Targeted delivery of apo(a)-specific antisense oligonucleotides to hepatocytes in vivo
    Biessen, EAL
    Vietsch, H
    Rump, ET
    Fluiter, K
    Bijsterbosch, MK
    vanBerkel, TJC
    ATHEROSCLEROSIS, 1997, 134 (1-2) : 357 - 357
  • [39] Development and Characterization of Antisense Oligonucleotides Against Human Rhinovirus for Efficient Prevention of Asthma Exacerbation
    Potaczek, D. P.
    Unger, S. D.
    Zhang, N.
    Taka, S.
    Michel, S.
    Akdag, N.
    Lan, F.
    Helfer, M.
    Hudemann, C.
    Eickmann, M.
    Skevaki, C.
    Megremis, S.
    Sadewasser, A.
    Alhamwe, B. Alashkar
    Alhamdan, F.
    Akdis, M.
    Edwards, M. R.
    Johnston, S. L.
    Akdis, C. A.
    Becker, S.
    Bachert, C.
    Papadopoulos, N. G.
    Garn, H.
    Renz, H.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2019, 199
  • [40] Oncogene-targeted antisense oligonucleotides for the treatment of Ewing sarcoma
    Maksimenko, A
    Malvy, C
    EXPERT OPINION ON THERAPEUTIC TARGETS, 2005, 9 (04) : 825 - 830