Dual-head gamma camera 2-[fluorine-18]-fluoro-2-deoxy-D-glucose positron emission tomography in oncological patients: Effects of non-uniform attenuation correction on lesion detection

被引:0
|
作者
Zimny, M. [1 ]
Kaiser, H.J. [1 ]
Cremerius, U. [1 ]
Reinartz, P. [1 ]
Schreckenberger, M. [1 ]
Sabri, O. [1 ]
Buell, U. [1 ]
机构
[1] Department of Nuclear Medicine, University Hospital, Aachen University of Technology, Pauwelsstrasse 30, D-52074 Aachen, Germany
关键词
Cameras - Diagnosis - Electrons - Fluorine - Glucose - Particle beams - Positrons;
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摘要
The purpose of this study was to evaluate a dual head coincidence gamma camera (DH-PET) equipped with single-photon transmission for 2-[fluorine-18]-fluoro-2-deoxy-D-glucose (FDG) imaging in oncological patients. Forty-five patients with known or suspected malignancies, scheduled for a positron emission tomography (PET) scan, were first studied with a dedicated ring PET and subsequently with DH-PET. All patients underwent measured attenuation correction using germanium-68 rod sources for ring PET and caesium-137 sources for DH-PET. Ring PET emission scan was started 64±17 min after intravenous administration of 235±42 MBq FDG. DH-PET emission followed 160±32 min after i.v. FDG. Attenuation-corrected and non-attenuation-corrected images were reconstructed for ring PET and DH-PET. The image sets were evaluated independently by three observers blinded to clinical data and to results of conventional imaging. Attenuation-corrected ring PET as the standard of reference depicted 118 lesions, non-attenuation-corrected ring PET 113 (96%) lesions, and attenuation-corrected DH-PET and non-attenuation- corrected DH-PET, 101 (86%) and 84 (71%) lesions, respectively (P20 mm, whereas attenuation correction increased the detection rate from 60% to 80% for lesions ≤20 mm (P
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页码:818 / 823
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