Porous hydroxyapatite template grown on self-assembly of lysozyme and saccharose and Langmuir-Blodgett thin films

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作者
Cavinatto, Daniela [1 ]
Zavaglia, Cecília A.C. [1 ]
Costa, Necesio [2 ]
机构
[1] Institute of Mechanical Engineering, Federal School of Itajubá, CP 55, Itajubá MG, Brazil
[2] Faculty of Mechanical Engineering, State University of Campinas, CP 6122, Campinas SP, Brazil
关键词
Atomic force microscopy - Biomaterials - Body fluids - Crystal growth - Crystal orientation - Electron beams - Interfaces (materials) - Langmuir Blodgett films - Porosity - Powder metallurgy - Thin films - Tissue;
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摘要
The methodology adopted on this work consists on producing an organic template with functional group and intermolecular distance defined by the Langmuir-Blodgett (LB) techniques. The functionalized substrates work orientating crystal growth of hydroxyapatite after being immersed in a solution simulating the body fluid at the body usual temperature. Electrons beams used in electronic microscopy can destroy the organic thin film. Based on that, the technique adopted on the characterization of the organic template and the hydroxyapatite film is the Atomic Force Microscopy. Porous and adhesive hydroxyapatite layers have been obtained, creating a good interface between the implanted material and the cellular tissue and also improving its bioactive and mechanical performance. It will certainly improve the performance of the prosthetic material when implanted.
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页码:99 / 102
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